Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

Agrobacterium-mediated transformation (AMT) has abundantly been used for scientific research for identifying valuable traits.

Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele

Studievoorlichting, Webinar

Promotor: Prof.dr. B. van de Water

Leiden University offers a unique range of summer courses where you can broaden or deepen your knowledge or share your expertise with fellow students. The choice of academic courses is very diverse, ranging from Law, Big Data, Languages and Linguistics to Maths and Natural Sciences, Biology, Biomedical…

This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

Our recent excavations have focused on the more recent New Kingdom/Late Period (ca. 1500-332 BCE) material.

The main theme of this thesis is the theoretical study of Gaussian processes as a tool in Bayesian nonparametric statistics.

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

Lezing, 5e Owada-leerstoel Symposium

Promotie

Politie, bestuurders en andere partijen kunnen vanaf nu beschikken over de adviezen van de nieuwe Wetenschappelijke Adviesraad Politie. Maartje van der Woude, hoogleraar Rechtssociologie, is een van de leden van deze raad.

Emeritus hoogleraar Natuurkunde Peter Kes is op 27 april 2012, de dag van de lintjesregen, benoemd tot Ridder in de Orde van de Nederlandse Leeuw.

Het P.J. Cosijn Research Fellowship is een initiatief om veelbelovende Research MA-studenten van de Universiteit Leiden met interesse in Angelsaksische studies de kans te geven onderzoek te doen naar Oudengelse taal- en letterkunde. De Cosijn Fellowships zijn onderdeel van het door ERC gefinancierde…

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

Promotor: Prof.dr. M. Schilthuizen

GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

This thesis advances our understanding of lipid uptake, a vital first step in lipid metabolism, by developing innovative click chemistry-based tools to study how immune cells internalize lipids.

Dissociative chemisorption is an important reaction step in many catalytic reactions.

Promotor: G. J. Kroes

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Volkomen overdonderd was prof.dr. Vincent Icke, toen burgemeester Henri Lenferink het woord tot hem richtte en hij in de gaten kreeg dat er iets bijzonders stond te gebeuren. Enkele minuten later speldde Lenferink Icke de versierselen op horend bij de benoeming tot Ridder in de Orde van de Nederlandse…

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Op woensdag 27 september 2017 heeft Henri Lenferink, burgemeester van Leiden, een gastcollege verzorgd voor de studenten van de Leidse masters Jeugdrecht, Bestuursrecht en Strafrecht.

Congres/symposium, Call for papers

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

Studievoorlichting

There are study programmes at LIACS that offer the opportunity to do an internship or research project, as part of the curriculum.

Lezing, Leiden Translation Talks

To study how planetary systems come into existence we study much younger systems still in formation.

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.