Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Systems are called real-time systems, if the correctness of the system does not only depend on the correctness of the system output but also on whether the output is delivered on time.

With tomography it is possible to reconstruct the interior of an object without destroying.

Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Ontdek de kracht van interdisciplinair AI-onderzoek bij het SAILS-initiatief van de Universiteit Leiden via dit tweewekelijkse seminar. Het SAILS-netwerk van AI-experts bestrijkt alle zeven faculteiten: Rechtsgeleerdheid, Wiskunde en Natuurwetenschappen, Archeologie, Sociale Wetenschappen, Geesteswetenschappen,…

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

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Promotor: R. Verpoorte, Co-promotores: Y.H.Choi, N.R. Mustafa

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Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman

Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…

We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.

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This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

This thesis focuses on the study of transient and variable radio sources in the universe.

Nout Wellink sprak over de rol van de centrale bank in het huidige roerige financiële klimaat. Daarbij gaat hij ook in op de gewijzigde kapitaaleisen die voor banken gelden.

Promotor: S.M. Verduyn Lunel

Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov

De incubatietijd (van infectie tot de eerste symptomen) en latente periode (van infectie tot de start van besmettelijkheid) zijn cruciaal voor het informeren van controle maatregelen aan het begin van een infectieziektenuitbraak. Een voorbeeld is de duur van quarantaine voor potentieel geïnfecteerden,…

Op 28 juni 2018 verdedigde Qiuyin Hu zijn proefschrift 'Regulating Working Conditions in Times of Globalization'. Het promotieonderzoek is begeleid door promotoren prof.dr. G.J.J. Heerma van Voss en prof. dr. B. Barentsen.

Promotor: S.M. Verduyn Lunel

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: H.Hoekstra

Op 29 januari 2019 verdedigde Robbert van Eijk proefschrift 'Web Privacy Measurement in Real-Time Bidding Systems, A Graph- Based Approach to RTB system classification'. Het promotieonderzoek is begeleid door promotor prof. dr. H.J. van den Herik.

Simon Willmetts levert bewijs voor een systematisch beleid van directe samenspanning tussen Time Inc. en de CIA

Het Hazelhoff Centre for Financial Law onderzoeksprogramma voor 2020-20203 draait om de integriteit van financiële markten in tijden van crisis en de mogelijke manieren om deze integriteit te bewerkstelligen.

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

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Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

In this thesis, I studied the origin and evolution of the non-thermal radiation in merging galaxy clusters.

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

Emoties spelen een cruciale rol in de EU-politiek. Dit artikel onderzoekt hoe emoties de EU-reactie op internationale crises door normovertredingen beïnvloeden.

De Leidse geesteswetenschappen staan in de top van de Times Higer Education Ranking. Dit jaar behaalden ze de 26e plek.