Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

Volg een keuzevak in beeldende kunst, design of muziek!

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

De Universiteit Leiden is een internationaal georiënteerde en brede universiteit. We onderscheiden vijf wetenschapsdomeinen waarbinnen ons onderzoek en onderwijs plaatsvindt.

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…

Een van de kernthema’s in het aanbod van CPL is ‘’internationale betrekkingen’.

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

Jan Crijns heeft samen met Renée Kool (Universiteit Utrecht) het strafrechtelijke preadvies van de Nederlandse Juristen-Vereniging geschreven, getiteld ‘Afscheid van de klassieke strafrechtelijke procedure?' Dit preadvies wordt - samen met de civielrechtelijke en bestuursrechtelijke preadviezen - gepresenteerd…

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

Eind november 2014 presenteerde Peter Meel zijn biografie van Henck Arron in Amsterdam, en in januari 2015 in Paramaribo.

Dit proefschrift onderzoekt de noodzaak van het creatief denken en experimenteren in het uitvoeren van complexe muziek in de late twintigste- en vroege eenentwintigste eeuw.

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…

Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

In dit artikel, gepubliceerd in het Nederlands tijdschrift voor Europees recht, bieden dr. J.E. Larik en prof. R.A. Wessel (Rijksuniversiteit Groningen) een kritische analyse van de handels- en samenwerkingsovereenkomst (HSO) die sinds 2021 de hoeksteen van de post-Brexit betrekkingen tussen de Europese…

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Promotor: W. Jiskoot, Co-promotor: H.A. Every

Boek over de totstandkoming van het Koninkrijk der Nederlanden, onder redactie van onder andere Henk te Velde.

This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Nu je weet wat de toelatingsvoorwaarden zijn van Midden-Oostenstudies is het tijd om de aanmelddeadlines te checken.

Heb je nog vragen over de master Notarieel recht? Neem dan gerust contact met ons op!

Wil jij de bachelor opleiding Italiaanse taal en cultuur studeren in Leiden? Bekijk de opleidingsvideo voor meer informatie.

Nu je weet wat de toelatingsvoorwaarden zijn van Latijns-Amerikastudies is het tijd om de aanmelddeadlines te checken.

Promotor: Prof.dr. M. Danhof

In het Leids Universitair Behandel- en Expertise Centrum (LUBEC) werken Klinisch (neuro)Psychologen, GZ-psychologen en Orthopedagoog-Generalisten. Zij bieden multidisciplinaire diagnostiek op maat.

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Deze uitgave gaat over de ontwikkeling van het trotskisme in Nederland van 1938 tot nu.

Promotor: G.R. de Snoo

Als je weet wat de toelatingsvoorwaarden zijn van de bacheloropleiding Filosofie is het tijd om de aanmelddeadlines te checken.

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

Heb je nog vragen over Informatica? Neem dan gerust contact met ons op!

Het Central Innovation District (CID) vormt het economisch hart van de stad Den Haag .

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.