The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…

For optimization problems, it is often unclear how to choose the most appropriate optimization algorithm. As such, rigorous benchmarking practices are critical to ensure we can gain as much insight into the strengths and weaknesses of these types of algorithms.

Indo-European is the name of the language family to which English belongs, along with many sub-families such as Germanic languages and Romance languages. In this course, you will delve into the structure and origins of these branches, the oldest languages belonging to the language family, linguistic…

Taalkundige Marian Klamer, verbonden aan het Leiden University Centre for Linguistics en het Leiden University Institute for Area Studies, is een van de 31 wetenschappers die van het NWO een Vici-subidie gekregen heeft voor haar onderzoeksproject 'Taal als tijdmachine'.

Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.

Book Launch

Lezing

Despite their ecological, cultural, and economic importance, lion (Panthera leo) populations in Kenya are declining rapidly due to retaliatory killings following livestock depredation, depletion of wild prey, habitat loss driven by human activities, climate change, and disease.

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Live meekijken met een CT-scan in plaats van achteraf de beelden pas te analyseren. Als het aan de Leidse wiskundige Jan-Willem Buurlage ligt, is dat binnenkort realiteit. Hij ontwikkelt methodes om de algoritmes achter 3D-scans sneller te maken. Best een uitdaging: ‘Net als wiskundigen zijn computers…

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

Reconstructie van de taalgeschiedenis door onderzoek naar taalverandering.

Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

Promotor: Prof.dr. E.F. Smets. Co-promotores: B. Gravendeel, F. Pupulin

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

Promotor: Prof.dr. E. Smets, M. Stech

Promotor: Prof.dr. P.C. van Welzen

Lezing, Lezingenreeks vergelijkende Indo-Europese taalwetenschap (VIET)

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…

Quantum computing represents a fundamentally new computational paradigm, capable of addressing problems that are intractable for classical computers.

Lezing

Promotie

Afgelopen week werd bekend dat Juliëtte Roding (LUCAS) en Odile Parsis (Université de Lille, Institut de recherches historiques du Septentrion) van de Frans-Nederlandse Academie een Van Gogh-grant hebben ontvangen voor het multidisciplinaire onderzoek: 'North(s) in Memory: Heritage, Museum dynamics…

How and to what extent the historic house (re-)constructs identity through image-making in China.

Medewerkers en studenten van het departement Archaeological Heritage and Society van de Faculteit Archeologie onderzoeken welke rol het verleden kan spelen in moderne samenlevingen. Zij willen meer weten over de relaties tussen verleden en heden, en de rol die erfgoed daarbij speelt.

In this dissertation non-parametric Bayesian methods are used in the application of robotic vision.

The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…

Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Een nieuw onderzoek van de Leidse archeologe Anastasia Nikulina en een internationaal team uit Frankrijk, Denemarken, het Verenigd Koninkrijk en Nederland, weerlegt het idee dat jager-verzamelaars vóór de opkomst van de landbouw een verwaarloosbare impact hadden op hun leefomgeving.

Lezing, This Time for Africa series

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

Aan de Universiteit Leiden worden cursussen over papyri en papyrologie aangeboden voor beginners en gevorderden (BA en MA), zowel op basis van teksten in vertaling als in de originele brontalen, van Egyptisch tot Grieks, Latijn en Arabisch.

Bestudeer alle aspecten van het menselijk leven in het verleden en plaats je kennis in een breder, historisch perspectief.

A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.