495 zoekresultaten voor “naar cognitive functions” in de Publieke website
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Evolutionary molecular dynamics
This thesis introduces the concept of
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On cluster algebras and topological string theory
My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.
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Galaxy formation and the structure of the Universe
Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)
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Knowledge extraction in the quantum random-oracle model
The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.
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Topological decoding of biomolecular fold complexity
Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…
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On Multifield Inflation, Adiabaticity and the Speed of Sound of the Curvature Perturbations
Promotor: A. Achúcarro, Co-Promotor: G.A. Palma
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Essentiality of conserved amino acid residues in β-lactamase
Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.
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Honoursonderwijs
Onderwijs voor nieuwsgierige en ambitieuze studenten die meer uit hun studie willen halen!
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Afgeleid eten en compensatiemechanismen
Een onderzoek naar de invloed van afgeleid eten op consumptiebeleving en het consumptiegedrag.
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Medicijngebruik door adoptiekinderen
Internationaal geadopteerde kinderen gebruiken niet meer medicijnen dan hun niet-geadopteerde leeftijdgenoten.
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Translation invariant Banach function spaces on groups
Promotie
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Wat werkt bij het voorkomen van sociale angst?
Programma's die de symptomen van sociale angst bij kinderen willen verminderen, omvatten doorgaans meerdere onderdelen, zoals blootstelling en mentale herstructurering. Het is onbekend of afzonderlijke onderdelen positieve effecten opleveren bij kinderen of dat een combinatie van onderdelen nodig is…
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The music of language: exploring grammar, prosody and rhythm perception in zebra finches and budgerigars
Promotor: C.J. ten Cate
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Jan Sleutels
Jan Sleutels is een Universitair hoofddocent aan het Instituut voor Wijsbegeerte.
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Theory of mind in language, minds, and machines: a multidisciplinary approach
Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.
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Omgang met regels
Welk effect heeft een verwerkingsvoorkeur op de omgang met regels?
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African Oral Literatures, new media and technologies
African oral literatures, new media and technologies: challenges for research and documentation
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Metals in LCIA
A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.
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Geïllustreerde handgeschreven archieven begrijpen
Veel handgeschreven en geïllustreerde archieven bevatten een schat aan informatie, maar worden weinig bestudeerd vanwege hun complexe en door computers moeilijk te ontcijferen inhoud. Het doel van dit project is een digitale omgeving te ontwikkelen die hier een oplossing voor biedt, en die de heterogene…
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The developing infant gut microbiota: mathematical predictions of the effects of oligosaccharides
A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.
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The stochastic geometry of non-Gaussian fields
Promotor: V. Vitelli, Co-promotor: J. Paulose
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Shaping Massive Galaxies: the structural evolution of galaxies across
Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.
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Risk bounds for deep learning
In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.
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Low energy electron transmission through layered materials and chiral organic films
In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…
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Metastability for low-temperature Kawasaki dynamics with two types of particles
Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi
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Algebraic techniques for low communication secure protocols
Promotor: R. Cramer
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Spin dynamics in general relativity
Promotor: J.W. van Holten
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Determination of surface formation energies on curved single crystals from STM images
In this thesis, we study different curved single crystals because of the diversity of surface structures across their curvature.
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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RAISE Onderzoek
Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…
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Semigroups on Spaces of Measures
Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille
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Substrate adaptability of β-lactamase
The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…
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Split Jacobians and Lower Bounds on Heights
This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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The optimization and scale-up of the electrochemical reduction of CO₂ to formate
Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Peeking into the future: Fungi in the greening Arctic
Promotor: E.F. Smets, Co-promotor: J. Geml
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Virus-host metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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The dynamic organization of prokaryotic genomes: DNA bridging and wrapping proteins across the tree of life
Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.
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Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
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From every angle: novel insights into CC chemokine receptor 2 pharmacology
The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.
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Discovery of BUB1 kinase inhibitors for the treatment of cancer
The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.
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On the 16-rank of class groups of quadratic number fields
Promotores: P. Stevenhagen, E. Fouvry (Univeriste Paris Saclay)
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Exploring the metabolism and toxicity of amino sugars and 2-deoxyglucose in Streptomyces
Streptomyces are prolific producers of enzymes and secondary metabolites, including more than 50% of all clinical antibiotics. This makes them highly attractive for medical, biotechnological, and industrial purposes.
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf