The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Zojuist verschenen: Nederlands internationaal privaatrecht Special issue: Private international law and finance

To get an idea of the science communication products and research that is possible, a few examples of student projects of recent years are shown below.

Hoe verwerken we taal en spraak? Hoe voegen we de informatie op verschillende niveaus – intonatie, zinsstructuur, betekenis, toon, woorden, klanken - samen? Hoe staat de informatie op het ene niveau in verband met informatie op een ander niveau?

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

In this research I assess the impact of the recently discovered gas reserves south off Cyprus on the escalation of the Cyprus conflict.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.

The thesis addresses the long-term dynamical evolution of hierarchical multiple systems.

Tuberculosis (TB) is associated with 1.5 million deaths annually. There is a need exists to optimize both current as well as novel antibiotic combination treatment strategies to improve the effectiveness and safety of treatments against TB.

Risk has become one of the defining features of modern society. This course examines various types of safety and security risks, and how these are perceived and dealt with in a wide array of professional and academic fields, ranging from criminology, counter-terrorism and cyber security, to philosophy,…

Image-Pro Plus, ImageJ, Cell Profiler, R, Knime en NIS-elements

Quantum annealing belongs to a family of quantum optimization algorithms designed to solve combinatorial optimization problems using programmable quantum hardware. In this thesis, various methods are developed and tested to understand how to formulate combinatorial optimization problems for quantum…

The aim of this thesis was to develop aluminium salt-based nanoparticles that may ultimately be used as adjuvant in human vaccines.

This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

Woensdag 7 september bezochten de nieuwe eerstejaarsstudenten Rechtsgeleerdheid en Criminologie de Stadsgehoorzaal voor een College Tour met als thema: Strafzaken en de media. Presentatrice Annemarie Brüning, bekend van Hart van Nederland, ging hierover in gesprek met professionals uit het vakgebied…

Lezing

We verwelkomen gastwetenschappers wier onderzoek aansluit bij onze uiteenlopende expertisegebieden. De tekst gaat verder in het Engels.

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

Deze opleiding wordt aangeboden door het Leiden Academic Centre for Drug Research en is gericht op onderzoek en ontwikkeling van geneesmiddelen. Het programma beslaat vrijwel het gehele gebied van het geneesmiddelenonderzoek en biedt studenten veel keuzevrijheid.

In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

This thesis investigates how non-genetic factors, such as inflammation and concomitant medication, impact hepatic drug metabolism and subsequent drug metabolizing phenotype predictions.

The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.

De Leiden Teachers’ Academy organiseert jaarlijks een symposium over onderwijsvernieuwing aan de Universiteit Leiden.

Promotor: T. Hankemeier, Co-promotor: R.J. Vreeken

Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

Voor je profielwerkstuk (PWS) ga je een eigen onderzoek doen. Een mooie voorbereiding op je latere studie! Wil je meer weten over hoe je dat aanpakt, of zoek je nog naar een onderwerp? Het Loket Profielwerkstukken biedt hulp in de vorm van informatie en inspiratie. Je kunt ons ook vragen stellen.&nb…

De BioMedical Metabolomics Facility Leiden (BMFL) biedt een zeer gestructureerde omgeving voor geavanceerd metobolomicsonderzoek. BMFL is gebaseerd op volledig gevalideerde, moderne platforms die gezamenlijk het gehele menselijke metabolisme beslaan.

The impact of the phenotypic plasticity of P. aeruginosa and the distinct CF lung microenvironments on antibiotic drug effects and resistance remains poorly understood.

The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?

Je kiest voor de studie Bio-Farmaceutische Wetenschappen wanneer je sterk geïnteresseerd bent in de ontwikkeling van en het onderzoek naar de werking van geneesmiddelen.

De Young Academy Leiden (YAL) is een selecte groep jonge academici aan de Universiteit Leiden. De YAL, opgericht in begin 2019, dient als platform om enthousiaste en ambitieuze jonge academici (post-PhD), die aan het begin van hun carrière staan, bij elkaar te brengen. YAL-leden vertegenwoordigen…

Ontdek het studentenleven bij de MSc Political Theory: Legitimiteit en Rechtvaardigheid aan Universiteit Leiden: studieverenigingen, activiteiten, academische gemeenschap en wonen in Leiden en Den Haag.

Hoe beïnvloedt de vernietiging van universiteiten in Gaza, ook wel 'scholasticide' genoemd, het wetenschappelijk leven en wat zijn de theoretische en juridische onderbouwingen van de term?

Onderzoekers vanuit verschillende vakgebieden werken samen om oplossingen te bedenken voor maatschappelijke problemen.

Hifadhi ya Dijiti ya Ustadh Mau

Promotor: P.M. Brakefield

Onderstaand een overzicht van alle vakken die door de afdeling Economie worden verzorgd.

Promotores: C.A.J. Knibbe, D. Tibboel, Co-Promotor: P. Bruins

Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman