Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

De eerste index om de veiligheid, duurzaamheid en circulariteit van producten te meten, waarmee ze het EU-kader (SSbD) operationaliseren.

This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

The vegetative growth period for leafy vegetables like lettuce is essential for yield and quality.

Over the past two centuries, socioeconomic development has improved material living standards but has also intensified environmental pressures, including climate change and biodiversity loss.

This thesis comprises the development of reproducible synthesis procedures for two-dimensional materials (composed of boron, nitrogen and carbon) on different metallic surfaces.

Stellar feedback is a crucial ingredient in the evolution of galaxies.

Dit artikel biedt een systematisch literatuuronderzoek van de belangrijkste principes, normen en strategieën van Security by Design en Privacy by Design.

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar

Hoe worden nachtruimtes verbeeld, geproduceerd, ervaren en verteld door migrantengemeenschappen in Europa? Dit onderzoeksproject onderzoekt deze vraag in acht Europese steden: Aarhus, Amsterdam, Berlijn, Cork, Galway, Lissabon, Londen en Rotterdam.

The majority (80%) of e-waste generated globally are recycled informally in developing countries.

It is time for the fifth lecture in the series Manuscript Mondays. We shall have two speakers. Jesse Keskiaho (University of Helsinki, Finland) will start with a talk about the soul. In the second talk Evina Steinova will tell us more about the medieval encyclopaedia. The talks will be followed by a…

My work focuses on a class of astronomical objects called protoplanetary disks.

In 2009-2010 ontstond in het westerse discours het idee van een meer ‘assertief’ China, een opvatting die China krachtig van de hand wijst. Niettemin is, vooral sinds Xi Jinping in 2012 aan de macht kwam, duidelijk dat China zijn lang gehanteerde buitenlandse beleidsdoctrine van ‘een lage profilering…

Stagemogelijkheden en opdrachten voor studenten*

Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.

De prijs wordt elke twee jaar op 10 december (Dag van de Rechten van de Mens) uitgereikt en geldt als erkenning voor wetenschappelijk werk op het gebied van internationale mensenrechten.

This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.

Op 15 april promoveert Shaoyu Wang. Het Leiden University Centre for Linguistics feliciteert Shaoyu!

In dit artikel onderzoeken de onderzoekers hoe solidariteit begrepen kan worden, rekening houdend met de diversiteit van verhalen, ruimtes, praktijken, lichamen en tijdsperiodes in een stad.

Why do sexual violence policies still fail to systematically address men and masculinities, when the need for cultural change among men has been central in public debates since #MeToo?

Leiden University Research & Innovation Services (LURIS), de afdeling van de Universiteit Leiden en het LUMC die de valorisatie van het wetenschappelijk onderzoek stimuleert en in goede banen leidt, presenteert op 28 oktober het boek Focus on the Appliance of Science from Leiden. Dat laat vanuit diverse…

Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.

Promotores:Th.J.C. van Berkel, M. van Eck

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.

Deze colleges zijn in het Engels, u kunt vragen stellen en reageren in het Nederlands.

What holds people together and what makes them willing to fit within larger political structures? Our project examines this question in the practices of dynastic rulership in Eurasia ca. 1300-1800.

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

Hifadhi ya Dijiti ya Ustadh Mau

Discover the unique Vital Interests course in the BSc Security Studies programme, featuring an inspiring session on climate diplomacy with Dutch UNFCCC negotiators.

Solliciteer nu voor de LUCIS Summer School on Philology and Manuscripts from the Muslim world. De summer school vindt plaats in Leiden van dinsdag 15 augustus 2017 tot en met vrijdag 25 augustus 2017. Solliciteren kan tot vrijdag 16 juni 2017.

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.

Promotor: Prof.dr. B. van de Water

Promotor: Prof.dr. J. den Hertog

Prof.dr. J. Memelink

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot

As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

Promotor: Prof.dr. J. Kuiper

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

Pancreatic ductal adenocarcinoma (PDAC) is among the cancers with the highest mortality rate, despite a relatively low incidence.