The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

M. Danhof, Co-promotores: J. Freijer, A. Yassen

“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.

België staat aan de vooravond van een hervorming van het Burgerlijk Wetboek. Ruben de Graaff adviseerde de commissie het internationale recht te erkennen als bron van verbintenissen. Zijn aanbeveling blijkt te zijn overgenomen.

Onderzoekreeks van de Afdeling Economie van de Universiteit Leiden op het raakvlak van economie en recht.

Dr. Bela Bode ontvangt van de Alexander von Humboldt-stichting de Feodor Lynen onderzoeksbeurs voor de ontwikkeling van nieuwe methoden voor verbetering van het signaal in de vaste stof NMR. Hij streeft naar een specifiek analytisch instrument voor oppervlakte-studies en onderzoek over membranen en…

Promotie

Promotie

Promotie

Van Lodewijk XIV tot Napoleon

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

Promotores: H. Schiessel, G.T. Barkema

Promotor: J. Schaye

A new publication on changes in the relationship between news and their public in Chile

Promotor: Prof.dr. C.W.J. Beenakker

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

Op 26 november 1940 hield Rudolph Pabus Cleveringa (1894-1980) zijn beroemd geworden protestrede.

De nieuwbouw voor de Faculteit der Wiskunde en Natuurwetenschappen is een belangrijke mijlpaal voor de Universiteit Leiden en de faculteit in het bijzonder. In drie fasen wordt een nieuw gebouw gerealiseerd. De eerste fase van het nieuwe gebouw is in 2016 in gebruik genomen en beslaat 45.000m2. Het…

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.

Promotor: Prof.dr. S.F. Portegies Zwart

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…

The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.

The way organisms develop from the initial single-cellular state to a complex final assembly like the human body, and how the final body is maintained throughout life, is one of the greatest mysteries and it’s understanding one of the biggest scientific challenges.

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

Promotor: Prof.dr. C.W.J. Beenakker

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

An interdisciplinary collection of the best international scholarship on Muslim youth.