The AT-Hook Nuclear Localized 15 (AHL15) gene belongs to a plant-specific gene family of DNA-binding proteins. Overexpression of AHL15 in Arabidopsis thaliana delays developmental phase transitions whereas its loss of function causes a slight acceleration.

With tomography it is possible to reconstruct the interior of an object without destroying.

Promotor: B. van de Water

Promotor: Prof.dr. E. F. van Dishoeck

Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

Marokko is een van de weinige landen in Noord-Afrika die aan de Arabische lente een vreedzame vorm heeft weten te geven door het pad van brede, gestage politieke hervormingen op te gaan. De Marokkaanse overheid verklaart de relatieve maatschappelijke rust daarnaast ook door haar islampolitiek, gericht…

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Promotor: S.M. Verduyn Lunel

Overlevingsanalyse is een onderzoeksgebied dat zich richt op het bestuderen van de tijd tot het optreden van een specifieke uitkomst.

This thesis is comprised of three chapters covering the theme of studying semistable varieties by looking at their dual combinatorial objects.

Human language is constantly evolving with its linguistic structure being shaped by language users at both individual and population levels. Focusing on the interplay between processes of language acquisition and communicative need in shaping human languages, this thesis introduces a novel computational…

In Mykeens Griekenland verschenen vanaf 1600 v. Chr. zeer veel monumentale bouwwerken zoals grote graftombes. Waarom stopte die bouwlust 400 jaar later abrupt? Archeoloog Ann Brysbaert onderzoekt de mogelijke oorzaken dankzij haar ERC Consolidator Grant.

Promotie

Promotie

The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.

Koen Keijzer plakte drie wiskundige rekenmodellen aan elkaar tot één model dat zinnige voorspellingen kan doen over hoe cellen bloedvaten vormen. Dat helpt biologen die onderzoek doen naar de rommelige, lekke bloedvaten in en om tumoren.

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

Onderzoeker Max van Duijn en promovendus Bram van Dijk passen taalmodellen toe op verhalen verteld door kinderen om zo hun inlevingsvermogen te onderzoeken. Voor dit onderzoek ontvingen zij de Best Paper Award tijdens de Computational Natural Language Learning conferentie in Singapore.

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

Promotor: W. T. F. den Hollander, F. H. J. Redig

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

Vandaag de dag liggen statistische methodes aan de grondslag van beslissingen in allerlei facetten van het leven, van de gezondheidszorg en agricultuur tot de financiële sector en marketing.

This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Statistiek-promovendus Daniël Gomon ontwikkelde statistische methoden die bijvoorbeeld medisch en demografisch onderzoek sterk kunnen verbeteren. ‘Wiskundigen houden niet van onrealistische aannamen.’ Gomon promoveert op 19 juni.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Dit proefschrift gaat over theoretische oppervlakte chemie binnen het veld van de heterogene katalyse.

Including modelling as part of software development appears to have various benefits.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

Sonja Boas ontwikkelde nieuwe technieken om het groeiproces van bloedvaten op computationele wijze te bestuderen. De resultaten van haar onderzoek geven een beter begrip van mechanismen in bloedvatgroei en dat is relevant voor de ontwikkeling van medische therapieën. Promotie op dinsdag 22 december…

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).