Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Op 28 en 29 augustus verzorgden Dr. Ben Van Rompuy aen Dr. Armin Cuyvers een tweedaagse training aan de commissarissen van de nieuw opgerichte Oost-Afrikaanse mededingingsautoriteit.

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Vanaf de koloniale tijd tot heden hebben grote aantallen Javanen hun woonplaats verlaten om zich in andere delen van Indonesië of veel verder weg te vestigen. Vaak was deze spreiding gedwongen, vaak met traumatische gevolgen.

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

This Thesis describes the synthesis of D-alanylated ribitol-based wall teichoic acids from S. aureus to probe their interaction with immune-binding partners.

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.

This dissertation presents new cryptographic protocols, which can be divided into two families.

In dit artikel onderzoeken Thijs van Dooremalen en Philip Smith hoe het publieke discours over hittegolven is verschoven in Britse kranten.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

Van de energietransitie in Namibië tot duurzame werkgelegenheid voor Nigeriaanse jongeren, van Afrikaanse kookboeken tot vodcasts over vintage Swahili pockets: tijdens een bezoek van het College van Bestuur etaleerden collega’s van het African Studies Centre Leiden en de African Library hun werk op…

The global agri-food system plays a critical role in food security and environmental issues.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

De Swahilikust kent een lange geschiedenis van transoceanische islamitische verbindingen die teruggaat tot de 25e eeuw. Toch heeft de boekdrukkunst de wereld veranderd; niet alleen de onze. In dit project worden unieke vormen en archieven van intellectuele geschiedenis ontrafeld die vanuit Zuid-Zuid-verbindingen…

Irene Khan, expert op het gebied van mensenrechten, werpt een aantal vragen op: Wat kan men verstaan onder een ‘Culture of Justice’? Wie bepaalt wat 'Justice' is? Hoe realistisch is de bevordering van ‘Rule of Law’ en ‘Justice’ in landen waar sprake is van ernstige conflictsituaties en armoede?

Promotor: Prof.dr. G.R. de Snoo

The main aim of this project is to reveal and unravel the invisible histories of the UN, transcending the dominant Western perspective to recover the historical agency of Global South actors. The research will investigate how the UN has both facilitated and limited their role in shaping global order…

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.

Afrika heeft een bevolking van 1,5 miljard mensen. In 2050 zal dit aantal naar verwachting stijgen tot 2,5 miljard. De impact van het continent op de wereldeconomie en samenlevingen, maar ook op het milieu, zal daardoor enorm toenemen.

Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.

Dit artikel levert een bijdrage aan een groeiend aantal onderzoeken naar radicalisering. Het richt zich specifiek op het onderscheid tussen individuen die radicalisering en daardoor betrokken raken bij terroristisch geweld en individuen die radicaliseren maar niet betrokken raken bij geweld.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…

De auteurs onderzoeken de afhandeling van cybermisdaadzaken door rechtshandhavers.

The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.