Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

Het Nederlands-Vlaams Instituut in Cairo (NVIC) is in 1971 opgericht. Negen universiteiten in Nederland en Vlaanderen participeren in het NVIC met als doel het stimuleren en internationaliseren van hun onderwijs- en onderzoeksactiviteiten in het Midden-Oosten. De beheervoerende instelling is de Universiteit…

Promotores: C.A.M.J.J. van den Hondel, V. Meyer, Co-promotor: A.F.J. Ram

The class-imbalance problem is a challenging classification task and is frequently encountered in real-world applications. Various techniques have been developed to improve the imbalanced classification performance theoretically and practically.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Promotor: Robert Tijdeman, Co-promotor: Cornelis Kraaikamp

Students Practicing Citizen Journalism

Computational thinking, programming, and algorithms form the basic of many of the things that are shaping our world, the way we work, interact, organize ourselves, and even spend our free time with social networks, streaming media, and games. And this transformation is far from being complete, it is…

How can we broaden youth participation in STEM Learning

Corruption, integrity (or a lack thereof…) and public values are near omnipresent elements in public administration and politics of all times. Cases of corrupt public officials and politicians continuously emerge. Strangely enough, however, it often remains unknown what actually occurred, how something…

When you have decided to participate in a Summer School of Leiden University, there are some matters you need to know before arrival. Please take a few minutes to read through the information here to find out what you can do from your side to smooth the process.

Studievoorlichting, Experience Day

Hieronder vind je de antwoorden op een aantal veelgestelde vragen over toelating tot de klinische specialisaties van de Master Psychologie.

De Leiden Slavery Studies Association (LSSA) is toegewijd aan het bevorderen van een beter begrip van slavernij en post-slavernij in elke periode en elk geografisch gebied.

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

Freshwater biodiversity has been threatened by eutrophication due to excessive nutrients in the environment. Releasing the freshwater species from such pressures requires efforts from industry and manufacturers to avoid emissions to vulnerable and high-risk regions.

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Timo Slootweg, associate professor at he department Philosophy of Law, published a chapter about Paul Scholten in

Promotores: Prof.dr. M. Franx, Prof.dr. M. Kriek (Univ. of California at Berkeley)

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

This thesis mainly focuses on multimodal understanding and Visual Question Answering (VQA) via deep learning methods. For technical contributions, this thesis first focuses on improving multimodal fusion schemes via multi-stage vision-language interactions.

This thesis is based on five papers on several topics.

Elke week organiseert ISGA de Research Seminar Series waarin onderzoek van zowel medewerkers van ISGA als van externen aan bod komt.

Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

Promotor: Prof.dr. M.T.M. Koper, Co-Promotor: F. Calle-Vallejo

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

Promotor: Prof.dr. G.P. van Wezel

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Galaxies in the Universe are distributed along the intricate framework of the Cosmic Web. Groups and clusters of galaxies comprise the densest regions in this network, and therefore, are excellent cosmic laboratories to study different aspects of galaxy evolution in extreme environments.

The thesis is about the study of shell evolution of the Hydrocenidae of the genus Georissa. This thesis started with a general overview on the evolutionary process of animals due to ecological changes.

De tweede geheel vernieuwde editie van 'The E-Primer' bespreekt hoe een breed scala experimenten kan worden geprogrammeerd in E-Prime 3. E-Prime is een van de meest gebruikte softwarepakketten voor het ontwerpen van psychologische experimenten.

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

This dissertation aims to advance understanding of amoeboid single cell migration under the influence of changing physicochemical environmental properties. The particular focus is on the relatively unknown influence of differing physical properties in the extracellular environment, such as the migratory…

Leiden University offers a unique range of summer courses where you can broaden or deepen your knowledge or share your expertise with fellow students. The choice of academic courses is very diverse, ranging from Law, Big Data, Languages and Linguistics to Maths and Natural Sciences, Biology, Biomedical…

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

Kunst en vrije tijd, Kunst en vrije tijd

Studievoorlichting

How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?

Learning a programming language is challenging. Even one of the first –but crucial– concepts to learn, variables, is hard to grasp. Variables can represent different roles and functions within a code and need to be named appropriately to support code comprehension and debugging.

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Een masteropleiding vergroot je kansen op de arbeidsmarkt en opent deuren naar uitdagende functies. Na je driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master aan de Universiteit Leiden of een andere instelling.