Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…

We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

Promotor: E.F. Smets Co-promotor: J. Geml

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Promotor: K.J. Batenburg

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.

Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

DSE 2.0: Naar een optimaal ontwerp van complexe, gedistribueerde cyber-fysieke systemen

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?

Promotor: Prof.dr. E. F. van Dishoeck

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Reducing greenhouse gas emissions is one of the most pressing challenges that humanity faces in the coming decades.

Neurolaw is een relatief jonge discipline, waarin de impact van de neurowetenschappen op het recht, de juridische praktijk en de criminologie wordt onderzocht. De actuele ontwikkelingen binnen de neurowetenschappen (neurobiologie, -psychologie en -psychiatrie) hebben de betekenis van onderzoek op dit…

Artin L-functions associated to continuous representations of the absolute Galois group G_K of a global field K capture a lot of information about G_K as well as arithmetic properties of K.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.

Promotores: P. Stevenhagen, L. van Geemen (Università degli studi di Milano), Co-Supervisor: Ronald M. van Luijk

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

The thesis addresses the long-term dynamical evolution of hierarchical multiple systems.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

The mission of our group is understanding how science communication works to improve the interaction between science and society. We believe better science communication can improve our society and engage many different groups with science, also improving science.

Promotor: Prof.dr. J.W.M. Frenken

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Promotores: A.P. IJzerman, H.W.T. van Vlijmen