This thesis investigates catalytic reactions at the atomic scale using scanning tunneling microscopy (STM), with a focus on Fischer–Tropsch synthesis, a key industrial process that converts hydrogen and carbon monoxide into liquid fuels.

The vegetative growth period for leafy vegetables like lettuce is essential for yield and quality.

Promotores: T.H. Oosterkamp, N. de Jonge

This thesis examines strategies to address the global threat of antimicrobial resistance (AMR). Antimicrobial resistance poses an increasing global health risk, highlighting the need for new treatments against Gram-negative pathogens.

Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

Promotor: Prof.dr. H.J.M. de Groot, Co-promotor: Francesco Buda

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.

Promotor: S.J. Edixhoven Co-promotor: L. van Geemen, P. Parent

The main object of study in this thesis is an Arakelov inequalitywhich bounds the degree of an invertible subsheaf of the direct image ofthe pluricanonical relative sheaf of a semistable family of curves.

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…

The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

Promotores: P. Stevenhagen, L. van Geemen Co-promotor: R.M. van Luijk

Optimally solving real-world expensive Black-Box Optimization (BBO) problems w.r.t. real-world constraints, such as wall-clock time and computational costs, is extremely difficult and tedious.

Vind jouw thuis bij LUC! Wij zijn gevestigd in het hart van Den Haag. Met ons eigen gebouw en internationale profiel biedt LUC een omgeving voor iedereen die op zoek is naar een interculturele ervaring en die een verantwoordelijke wereldburger wil worden.

Public Administration is a major refereed journal publishing articles on public administration, public policy and public management.

In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…

How can we broaden youth participation in STEM Learning

Despite their ecological, cultural, and economic importance, lion (Panthera leo) populations in Kenya are declining rapidly due to retaliatory killings following livestock depredation, depletion of wild prey, habitat loss driven by human activities, climate change, and disease.

Workshop

Workshop

In this thesis, we investigate how deep generative models (AI models that can create new designs) can be better utilized for technical and industrial design. Our goal is to generate designs that are not only realistic (plausible), but also efficient, reliable, and usable in complex 2D and 3D applica…

The global agri-food system plays a critical role in food security and environmental issues.

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.

In het academisch jaar 2023-2024 biedt het interdisciplinaire onderzoeksprogramma Sociale Veerkracht en Veiligheid vier vakken aan voor studenten die beginnen met het derde jaar van hun bachelor. Deze vakken zijn te volgen binnen de ruimte voor keuzevakken. Je kunt de vakken afzonderlijk als keuzevak…

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

Op 23 februari 2022 verdedigde Cale Davis het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. C. Stahn en dr. J.C. Powderly.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Promotor: M. Franx, Co-Promotor: I.F. Labbé

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

Promotores: J. Kok, M. Chaudron (Chalmers University)

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Understanding how nature captures and transfers solar energy is essential both for elucidating biological photosynthesis and for guiding the design of artificial light-harvesting systems.

The main topic of this PhD thesis is the Arakelov ray class group of a number field, an algebraic object that contains both the ideal class group structure and the unit group structure.

Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.

n this thesis we study curves. In the first half, we study moduli spaces of curves and Gromov-Witten invariants, certain kinds of curves counts. We employ logarithmic geometry for this.

Na het ontvangen van je diploma van LUC, kun je als alumni overal ter wereld heen. Velen die je voor zijn gegaan hebben ervoor gekozen om een master als vervolgopleiding te doen. Sommigen beginnen meteen aan hun professionele carrière of volgen een PhD. Door de vele academische vakgebieden die op LUC…

For questions and suggestions regarding the series, please contact prof. dr. Olaf van Vliet or dr. Max van Lent

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…