Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Wiskunde en Natuurwetenschappen, Sterrewacht Leiden (STRW)

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Studievoorlichting

Grensverleggend geschiedenis leren.

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

The Dutch atlas with pesticides concentrations in surface waters have been overhauled. This new, free accessible, website is in line with the European Framework Directive on Water (In Dutch: KRW).

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

How does the management of Elephant Marsh Fishery in Malawi relate to wider contexts of policies, theories and regions? And how can the current management system be adapted to achieve long-term sustainability of the fishery?

The project falls in the context of the EU Thematic Strategy on the Sustainable Use of Natural Resources (COM(2005)670). The Institute for Environment and Resources (IES) of the Joint Research Centre (JRC) has developed three sets of decoupling indicators. Such indicators require the definition of a…

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

Promotor: Prof.dr. E. F. van Dishoeck

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

This thesis is is made of three parts. The first part describes a generalization of the Chabauty's method, that can be used to determine the rational points of a curve such that s+g>r+1, where g is the genusof the curve, r is the rank of the Mordell-Weil group of the jacobian of the curve and s is…

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Geometric phases lead to a nontrivial interference result when an electron's different quantum mechanical paths choices encircle a magnetic coil in an Aharonov-Bohm experiment.

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot

Bet v1, the major allergen in birch pollen, is one of the main causes of allergies such as asthma and rhino-conjunctivitis. It is the main cause of birch pollen allergy in humans.

Promotor: Prof.dr. W.T.F. den Hollander

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.

Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…

Combinatorial games are games for two competing players, moving in a turn-by-turn fashion, in which there is no chance nor hidden information⁠. Chess, checkers and the simpler tic tac toe are well-known examples of this class of games, as well as game of go⁠.

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

The specialisation Science Communication and Society (SCS) concerns science communication in a broad sense. The program focuses on the link between science and society and covers knowledge and skills in the field of science communication.

Promotor: Roeland M.H. Merks

Gibbs measures, as used in Statistical Mechanics, have a definition that is remarkably similar to the definition ofg-measures, used in dynamical systems.

Promotor: S.J. Edixhoven

Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.

Let A be a commutative algebraic group over a field K, and let G be a finitely generated subgroup of the K-rational points of A. The purpose of this thesis is to study the degrees of the Kummer extensions relative to A,K and G.