Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.

This dissertation explores how we can make anomaly detection—identifying unusual or faulty behavior in complex systems—more trustworthy and effective, with a focus on smart manufacturing.

In this work, we attempt to answer the question:

Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

In the era of big data, extracting insights from complex datasets is a key challenge. This thesis demonstrates the superiority of graph-based methods over traditional clustering (e.g., k-means, DBSCAN) and outlier detection for analyzing high-dimensional and noisy data.

Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

Promotor: E. Bouwman, Co-Promotor: S. Bonnet

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

Mycorrhizas are symbiotic associations between soil fungi and most plant species.

Op 8 januari 2020 verdedigde Jelmer Brouwer zijn proefschrift 'Detection, detention, deportation'. Het promotieonderzoek is begeleid door promotoren prof.dr. J.P. van der Leun en prof.dr. M.A.H. van der Woude.

Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

This thesis describes how complex and real-world relevant analytical solutions can be found starting from a simple Nagumo problem posed on one or two-dimensional lattices.

We consider the propagation of electrical signals through nerve fibres.

Promotor: I. Snellen, Co-Promotor: M. Kenworthy

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

Cardiovascular diseases (CVDs) are the leading global cause of mortality. Endothelial dysfunction, an early reversible stage of CVD development, is marked by decreased nitric oxide production linked to Ca2+ influx in endothelial cells.

Promotor: G.R. de Snoo, Co-promotor: C.J.M. Muster

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Miles Kellerman, universitair docent aan de Universiteit Leiden, stelt dat overheden financiële criminaliteit beter kunnen opsporen door Licensed Detection Agents in te zetten, een soort bounty hunters die structurele tekortkomingen in bestaande detectiesystemen moeten oplossen.

In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…

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This thesis investigates the application of deep learning techniques in image analysis across various domains, focusing on four main themes: feature extraction, classification, segmentation, and integration, demonstrating the transformative potential of these technologies.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

With the conference circuit slowly reopening after Covid forced almost all academic interactions online, thousands of conference attendees descended on Brussels for Europe’s largest technology conference. eLaw’s annual sponsorship of one of the many CPDP conference panels brought a diverse range of…

Transport inspectorates are looking for novel methods to identify dangerous behavior, ultimately to reduce risks associated to the movements of people and goods. We explore a data-driven approach to arrive at smart inspections of vehicles.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

In the first part of this thesis we study the geometry of folding patterns.

Promotor: A.W. van der Vaart

Promotor: Arjen Doelman, Co-promotor: Vivi Rottschäfer

Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Software development is a complex process. It is important that software products become stable and maintainable assets.

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

The thesis is part of a bigger project, the HEPGAME (High Energy Physics Game). The main objective for HEPGAME is the utilization of AI solutions, particularly by using MCTS for simplification of HEP calculations.

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

Promotores: J. Kok, M. Chaudron (Chalmers University)

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

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