983 zoekresultaten voor “discovered of the year” in de Publieke website
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abilities in children with sex chromosome trisomy (XXY, XXX, XYY) aged 1–6 years
Een goede taalontwikkeling is van belang voor de cognitieve en sociale ontwikkeling, om te kunnen communiceren en om te kunnen leren. Als de taalontwikkeling niet verloopt zoals verwacht, kan dit allerlei consequenties hebben. Kinderen met een extra X of Y chromosoom hebben een verhoogd risico op problemen…
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Dawn of the red and dead: stellar kinematics of massive quiescent galaxies out to z = 2
Promotores: Prof.dr. M. Franx, Prof.dr. M. Kriek (Univ. of California at Berkeley)
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Five years after Covid‐19: What have we learned (and forgotten)?
Dit artikel blikt vijf jaar na dato terug op de lessen van de COVID-19-pandemie. De crisis legde kwetsbaarheden bloot in zorgsystemen, bestuur en sociale samenhang.
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Studies of dust and gas in the interstellar medium of the Milky Way
Promotor: Prof.dr. A.G.G.M. Tielens
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Tracing the journey of the sun and the solar siblings through the Milky Way
Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown
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Fisheries in the Waza Logone Floodplain. An Analysis of the Status of the Fisheries Sector and Mitigation of Conflicts within the Sector in North
Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh
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Sugoi! Leiden Asia Year van start op dies
Een jaar lang staat Leiden in het teken van Azië met talloze Aziatische evenementen, conferenties, tentoonstellingen en concerten. Aanleiding is de nieuwe Asian Library van de Universiteit Leiden. Kom lezen, kijken, luisteren, proeven of dansen zoals ze dat doen in Bollywood of Indonesië.
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The application of the United Nations Convention on the Rights of the Child by national courts
Op 3 december 2019 verdedigde Meda Couzens haar proefschrift 'The application of the United Nations Convention on the Rights of the Child by national courts'. Het promotieonderzoek is begeleid door promotoren prof.dr. T. Liefaard en prof.mr. J.J. Sloth-Nielsen.
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Extracellular Matrix Mechanics in the Regulation of the early steps of the Metastatic Cascade
Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.
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Structural characterization of the cell envelope of Actinobacteria under changing environments
Bacteria have the ability to alter their morphology in order to adapt to changing environments.
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The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
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Mechanistic studies of the water oxidation reaction with molecular iron catalysts
In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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Online Course Anatomy of the Abdomen and the Pelvis: a journey from basic to clinic
In this course, you will explore the organs involved in our food digestion and discover the common causes of abdominal and pelvic pain. The latest graphics and animations will give you new insights and understandings of this part of the body.
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From Star-formation to Recombination: Expanding our View of the Radio-Recombination-Line Universe
The origin and evolution of galaxies are closely tied to the cyclic feedback processes between stars and the interstellar medium (ISM).
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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2017: Leiden Asia Year. Kom met ideeën!
Het Leiden Asia Year komt eraan. 2017 staat bij de universiteit en in de stad helemaal in het teken van Azië . Heb je ideeën om het programma nog mooier te maken? Meld ze bij de universiteit!
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On Multifield Inflation, Adiabaticity and the Speed of Sound of the Curvature Perturbations
Promotor: A. Achúcarro, Co-Promotor: G.A. Palma
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Structure and substructure in the stellar halo of the Milky Way
Promotor: K.H. Kuijken
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Far from home: the science exploitation of the fastest Milky Way stars
The Sun and all the stars in the night sky reside in the Milky Way galaxy. In the at-rest reference frame of the Galaxy, typical stars travel with velocities of about 100-200 kilometres per second.
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The structure of the cytochrome P450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography
Promotor: Prof.dr. M. Ubbink
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Aria of the Dutch North Sea
Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn
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Changing the Nature of the Beast
Op de eerste dag van jouw nieuwe baan heb je zweethanden, ben je nerveus en onzeker, maar een paar maanden later zijn die gevoelens al weer verdwenen. Je hebt jouw nieuw rol eigen gemaakt en je bent nu onderdeel van de organisatie. Het proces dat daar naar toe leidt heet
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The Role and Effectiveness of the G20
The Role and Effectiveness of the G20. In dit artikel, gepubliceerd in The Changing Global Order onderdeel van the United Nations University Series on Regionalism book series, bespreekt auteur Jaroslaw Kantorowicz de evolutie van de G20.
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Invariant Hilbert subspaces of the oscillator representation
Promotor: G. van Dijk
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Becoming Literate by Means of the internet
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The material side of the energy transition: analyzing flows and stocks of critical and other metals
The expanding population and economic activity are driving up global energy consumption. Simultaneously, there is an urgent need to transition from fossil fuels to renewable sources to mitigate the climate crisis, primarily caused by fossil fuel combustion.
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Explicit Computation of the Height of a Gross-Schoen Cycle
Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.
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Regulation of the arabidopsis AGC kinase PINOID by PDK1 and the microtubule cytoskeleton
Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.
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Chemistry and characterization of the graphene basal plane and edge for recognition tunneling
Biopolymer sequencing with graphene edge-based tunnel junctions has the potential to overcome current limitations with the third generation of sequencing based on biological nanopores.
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Lost in translation: The toll-like receptor 7 induced pharmacological challenge model of the skin
This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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The Role of the Domestic Law of the Host State in Determining the ratione materiae Jurisdiction of Investment Treaty Tribunals: The Partial Revival
Op 19 december 2019 verdedigde Reza Eftekhar zijn proefschrift 'The Role of the Domestic Law of the Host State in Determining the ratione materiae Jurisdiction of Investment Treaty Tribunals: The Partial Revival of the Localisation Theory'. Het promotieonderzoek is begeleid door promotor prof.dr. E.…
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Aspects of the analysis of cell imagery: from shape to understanding
In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Winds in the AGN environment: new perspectives from high-resolution X-ray spectroscopy
Promotor: J.S. Kaastra Co-promotor: E. Constantini
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developments in automated structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu
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CfP: 25 Years after Hillenbrand (Groningen, 10-12 October)
On 10-12 October 2024, a workshop is held at the University of Groningen, titled: "25 years after Hillenbrand: New Approaches to Sources, Translation and Perspectives". The organisers aim to gather specialists and early career researchers in the field of crusader studies to discuss emerging research…
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Novel role of the AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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Vooruitkijken naar ‘The Next Ten Years’ bij LDE-jubileumbijeenkomst
De strategische alliantie Leiden-Delft-Erasmus Universities bestaat tien jaar in 2022. Tijdens de jubileumbijeenkomst ‘The Next Ten Years’ in de Faculty Club op 12 april keken de partners terug op wat er bereikt is en werd er vooruitgekeken naar de grote maatschappelijk uitdagingen van de komende tien…
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Dyslipidemia at the crossroad of the skin barrier and the arterial wall
The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…
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The optimization and scale-up of the electrochemical reduction of CO₂ to formate
Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…
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The developing infant gut microbiota: mathematical predictions of the effects of oligosaccharides
A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.
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In vitro investigation of the photoprotection mechanism of Light Harvesting Complex II
Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.
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Modelling the dynamics of the innovation process: a data-driven agent-based approach
Promotor: Prof.dr. B.R. Katzy
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Chemical functionalization of the graphene surface for electrical and electrochemical sensing application
Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.
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Fungi of the greening Arctic: compositional and functional shifts in response to climatic changes
Promotor: E.F. Smets Co-promotor: J. Geml
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On the nature of the right to resist: a rights-based theory of the ius resistendi in liberal democracies
Op 7 september verdedigde Francesc Claret Traid het proefschrift 'On the nature of the right to resist: a rights-based theory of the ius resistendi in liberal democracies'. Het promotieonderzoek is begeleid door Afshin Ellian en Gelijn Molier.