1,095 zoekresultaten voor “effects of prison sente de” in de Publieke website
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Erik Bahre on Dutch radio about the effects of the Russia-Ukraine grain agreement on Africa
Economic Anthropologist Erik Bähre talks on the Dutch News Radio Channel BNR about the effects of the Russia-Ukraine grain agreement for African countries.
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Exploring structure dependencies of gas-surface interactions with curved single crystals
Curved single crystals provide variable, but well-defined surface structures.
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Peeking into the future: Fungi in the greening Arctic
Promotor: E.F. Smets, Co-promotor: J. Geml
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Nanomaterial safety for microbially-colonized hosts: Microbiota-mediated physisorption interactions and particle-specific toxicity
The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.
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Creating Global Scenarios of Environmental Impacts with Structural Economic Models
To limit the effects of climate change, global average temperature since pre-industrial measurements are to be kept well below 2 °C preferably even at 1.5 °C.
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Modelling the interactions of advanced micro- and nanoparticles with novel entities
Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.
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North Sea noise in the Anthropocene: an impact study of human-made impulsive sounds on free-ranging cod
Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.
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Open label placebo voor jeuk
Positieve verwachtingen kunnen het gevoel van jeuk beïnvloeden en placebo-effecten oproepen, terwijl negatieve verwachtingen nocebo-effecten bij jeuk kunnen veroorzaken. Er zijn aanwijzingen dat placebo-effecten ook kunnen optreden wanneer mensen weten dat zij een placebo innemen. Er is weinig bekend…
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Online Course The Great Sustainability Transition
In this course, you will learn about sustainability and staying with the environmental boundaries of our planet. You will gain an understanding of the effects of growing affluence and population growth, the key challenges we are facing, and ways to influence your direct environment.
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in Advancing Accountability for Atrocity Crimes: Legal Powers and Effects
Op 20 oktober 2021 verdedigde Michael Ramsden het proefschrift 'The Role of the United Nations General Assembly in Advancing Accountability for Atrocity Crimes: Legal Powers and Effects'. Het promotieonderzoek is begeleid door promotor prof.dr. N.M. Blokker.
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selected methodological and data challenges while accounting for rebound effects
To conclude, this thesis provides valuable methodological insights to address data gaps and improve environmental impact assessments within the circular economy, with a particular focus on product reuse and sharing practices. Through empirical analysis and innovative approaches, it aims to support informed…
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Surface Temperature and the Dynamics of H2 on Cu(111)
Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…
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Knowledge extraction in the quantum random-oracle model
The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.
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The impact of climate variability on the ecology of a lion (Panthera leo Linnaeus 1758) population and lion livestock conflicts in the Amboseli
Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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Turtles all the way down: multiscale simulations connecting star and planet formation
The formation of stars and planets happens over multiple scales, which can interact. In particular, planet formation happens in the dense, complex environment of star forming regions.
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Publicatie artikel “Social support at work and at home: Dual-buffering effects in the work-family conflict process”
Dr. Helen Pluut heeft een artikel gepubliceerd in het gerenommeerde tijdschrift Organizational Behavior and Human Decision Processes (OBHDP) in samenwerking met Remus Ilies (National University of Singapore), Petru Curşeu (Open Universiteit en Babeş-Bolyai University) en Yukun Liu (University of Western…
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Disorder and interactions in high-temperature superconductors
This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.
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Learning from nature: using plant-soil feedback principles to improve growth and health of a horticultural crop
Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…
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When galaxy clusters collide: the impact of merger shocks on cluster gas and galaxy evolution
Promotor: Prof.dr. H.J.A. Rottgering
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Monitoring drought and salinity stress in agriculture by remote sensing for a sustainable future
Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…
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Harnessing zebrafish xenograft models for ocular melanoma treatment discovery
The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…
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The role of zebrafish larvae for studying anxiety-like behaviour
The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.
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Impact of nitrogen fertilization on the soil microbiome and greenhouse gas emission
The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.
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Dancing with the Stars
This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.
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From stress to success; How actinobacteria exploit live without a cell wall
The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.
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The power of biotic ligand models : site-specific impact of metals on aquatic communities
Promotor: G.R. de Snoo, Co-promotores: M.G. Vijver, J.P.M. Vink
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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De effecten van stress en angst op nocebo hyperalgesie
Welke rol spelen stress en angst bij de vorming van nocebo hyperalgesie?
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Sofie RasmussenFaculteit der Wiskunde en Natuurwetenschappen
a.s.b.rasmussen@cml.leidenuniv.nl | 071 5272727
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Investigating lipid formulations for efficient RNA delivery using zebrafish models
Lipid formulations have demonstrated strong potential for nucleic acid delivery,particularly with the success of COVID-19 vaccines. Despite these advances, manyaspects of lipid formulations remain unclear.
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Weighing the Dark: Cosmological Applications of Gravitational Lensing
Promotor: K. Kuijken, Co-Promotor: H. Hoekstra
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The noisy underwater world: the effect of sound on behaviour of captive zebrafish
Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn
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Hunting dark matter with X-rays
Promotor: A. Achúcarro Co-promotor: A. Boyarsky
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Monsters in the Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Onderzoeksgroep Geweld en Geweldpreventie (Violence and Violence Prevention)
Bij de Onderzoeksgroep Geweld en Geweldpreventie (Violence and Violence Prevention) wordt onderzoek gedaan naar de complexiteit van hedendaags geweld, de uiteenlopende verschijningsvormen ervan en strategieën voor preventie.
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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Exploring Grainyhead-like 2 target genes in breast cancer
The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.
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The stochastic geometry of non-Gaussian fields
Promotor: V. Vitelli, Co-promotor: J. Paulose
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Afdeling Environmental Biology (CML-EB)
De afdeling Environmental Biology (CML-EB) houdt zich bezig met vraagstukken rondom biodiversiteit en natuurlijke hulpbronnen op het platteland in westerse en niet-westerse gebieden.
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Caging ruthenium complexes with non-toxic ligands for photoactivated chemotherapy
The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.
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Functional analysis of Dof transcription factors controlling heading date and PPDK gene expression in rice
Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang
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Microstructural and Metabolic Alterations in the Zebrafish Brain Induced by Toll-Like Receptor 2 Deficiency
Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.
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Biophysical studies of intracellular and cellular motility
This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Aria of the Dutch North Sea
Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn