246 zoekresultaten voor “oort able” in de Publieke website
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Synthesis and application of glycans unique to S. Mansoni
Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.
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Rationally designed peptide based functional biomaterials
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
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Kearifan Kesehatan Lokal: indigenous medical knowledge and practice for integrated nursing of the elderly with cardiovascular disease in Sumedang
The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.
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Neutrinos From the Milky Way
Promotor: Prof.dr. M. de Jong
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Identification and characterization of viral Xrn1-resistant RNAs
Several single-stranded RNA viruses make use of Xrn1-resistant RNAs in their 3’ untranslated regions of their genome RNAs in order to increase their pathogenicity.
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Understanding the Heterogeneity of Corporate Entrepreneurship Programs
In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…
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Emergence of Linguistic Universals in Neural Agents via Artificial Language Learning and Communication
Human language is constantly evolving with its linguistic structure being shaped by language users at both individual and population levels. Focusing on the interplay between processes of language acquisition and communicative need in shaping human languages, this thesis introduces a novel computational…
- English Language Assessment for BA and MA students
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In vogelvlucht
De oudste universiteit van Nederland werd opgericht op 8 februari 1575 in de Leidse Pieterskerk. Dit gebeurde tijdens de Tachtigjarige Oorlog, de opstand van de noordelijke provincies tegen de Spaanse overheersing.
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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On metrics and models for multiplex networks
In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.
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Studies on molecular basics of metabolic syndrome in zebrafish
The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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spFRET studies of nucleosome dynamics modulated by histone modifications, histone variants and neighboring nucleosomes
Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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Synthetic, Physical and Computational Chemistry of Propeller-shaped Polycyclic Aromatic Hydrocarbons
This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…
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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Understanding disease suppressive soils
Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.
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Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands
Promotores: A.P. IJzerman, H.W.T. van Vlijmen
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Contact
Locatie
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Public Outreach
De Astronomy & Society Group van de Sterrewacht Leiden brengt het publiek in contact met de wonderen van het heelal en deelt wetenschappelijke, technologische, culturele en educatieve aspecten van de sterrenkunde met de samenleving.
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Transfer Learning in Deep Reinforcement Learning and Procedural Content Generation
In this dissertation (titled: Exploring the Synergies between Transfer in Reinforcement Learning and Procedural Content Generation) we explore how the two research fields named in the title, namely Transfer in Reinforcement Learning (TRL) and Procedural Content Generation (PCG) can synergize togethe…
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Structured Parallel Programming for Monte Carlo Tree Search
The thesis is part of a bigger project, the HEPGAME (High Energy Physics Game). The main objective for HEPGAME is the utilization of AI solutions, particularly by using MCTS for simplification of HEP calculations.
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Workshop: How to write a Data Management Plan (DMP)
Workshop
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Workshop: How to write a Data Management Plan (DMP)
Workshop
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Searching by Learning: Exploring Artificial General Intelligence on Small Board Games by Deep Reinforcement Learning
In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…
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The aging B cell landscape in atherosclerosis
In this thesis, single-cell approaches were applied to characterize the impact of aging on the immunological B cell landscape in different models of atherosclerotic cardiovascular disease, with the goal to identify and study new B cell-associated biomarkers and therapeutic targets to halt atherosclerosis…
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Workshop: How to write a Data Management Plan (DMP)
Workshop
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Finding Baby Black Holes with the James Webb Space Telescope
Lezing, Oort lecture
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Locaties toen en nu
Met haar beeldbepalende gebouwen is de universiteit overal in de stad Leiden terug te vinden. De universiteit heeft een duidelijke stempel gedrukt op de Leidse museumcollecties.
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Privérondleidingen
Naast de inlooprondleidingen in het bezoekerscentrum bieden wij ook privérondleidingen voor groepen aan. Deze rondleidingen gaan dieper in op de geschiedenis van het gebouw, maar bieden ook de mogelijkheid om meer te leren over sterrenkunde in het algemeen.
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Onderzoek
Research
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De Kolyvan-Voskresensk Fabrieken en de Russische Integratie van Zuid-Siberië, 1725-1783
How were the Russians, under early modern conditions, able to incorporate this distant, undeveloped and, because frequent nomadic attacks, dangerous territory? And what role did the Kolyvan-Voskresensk plants play in this process?
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Na je studie
Afgestudeerden van de bachelor Security Studies aan de Universiteit Leiden hebben toegang tot diverse masterprogramma's en uitstekende carrièrekansen. Ontwikkel je als beveiligingsstrateeg en vergroot je kansen op een succesvolle carrière in zowel de publieke als private sector.
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Master Track Public Administration: Economics and Governance
The Economics and Governance specialisation of the Master in Public Administration teaches you to formulate problem-solving approaches to concrete policy issues found at the intersection between economics and public administration. This specialisation is a unique joint offering of the Department of…
- Do Communities Build Monuments or Do Monuments Build Communities?
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Internships
There are study programmes at LIACS that offer the opportunity to do an internship or research project, as part of the curriculum.
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Over de faculteit
De faculteit biedt een internationale academische omgeving met 36% van de studenten, promovendi en onderzoekers uit het buitenland.
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PhD Thesis Pieter Boonstra
Pieter Boonstra (RUG) will defend his PhD thesis (Reading by example. The communication of religious knowledge in the collationes of the Brothers of the Common Life) on Thursday, 2 September 2021, at 14:30. Pieter was part of the NWO-funded research project 'Communication and Exploitation of Knowledge'…
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Leidse astronomen rekenen geschiedenis Oortwolk voor het eerst helemaal door
Het is een team van Leidse astronomen gelukt om de eerste 100 miljoen jaar van de geschiedenis van de Oortwolk door te rekenen. Tot nu toe waren alleen stukjes van de geschiedenis los van elkaar bestudeerd. De wolk met zo'n 100 miljard komeetachtige objecten vormt een enorme schil aan de rand van ons…
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ALMA: sterrenkundige doorbraken met Leidse inbreng
Sterrenkundige Ewine van Dishoeck stond aan de wieg van ALMA, de grootste radiotelescoop ter wereld. Op 13 maart 2013 was de officiële ingebruikname. Vanaf de basis in Chili kan nu het ontstaan van planeten worden waargenomen.
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Radio Weetlust interviewt Leidse wetenschappers tijdens Leiden2022
Leiden is in 2022 een heel jaar lang European City of Science, met elke dag een ander dagonderwerp. Het radioprogramma Radio Weetlust besteedt elke dag aandacht aan dat onderwerp, samen met interessante gasten. Verschillende Leidse wetenschappers zijn al door het radioprogramma geïnterviewd.
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Nieuwe masterspecialisatie Economics & Governance
New master specialisation: Economics and Governance
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Maartje Draak Seminars (Utrecht, 27-28 June)
By virtue of the legacy of prof. Maartje Draak, which is administered by the Royal Netherlands Academy of Arts and Sciences, the Celtic Studies section of Utrecht University is able to organise the Maartje Draak Seminars in which international Celticists visit Utrecht for intensive workshops and sem…
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50ste verjaardag van de ontdekking van quasars door Leidse doctor Maarten Schmidt
Op 16 maart 1963, publiceerde Maarten Schmidt, een Leidse doctor die op dat moment werkte aan het California Institute of Technology, een artikel dat flink wat opschudding veroorzaakte in de astronomische wereld. De lichte kleine radiobronnen die onlangs waren ontdekt, bleken geen onbekende sterren…
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Grote belangstelling voor Proefstuderen
Zo’n 800 bezoekers, waaronder ongeveer 550 scholieren en 250 begeleiders, hebben zich aangemeld voor Proefstuderen (voorheen Open Dag op Locatie) dat op vrijdag 28 november plaatsvindt op de faculteit. Tijdens deze voorlichtingsdag kunnen scholieren zich verdiepen in onze bacheloropleidingen en de sfeer…
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Universiteitsgeschiedenis compleet: Otterspeer presenteert vierde deel
Op de dies natalis presenteerde hoogleraar Universiteitsgeschiedenis Willem Otterspeer het vierde en laatste deel van zijn boekenreeks over de geschiedenis van de Universiteit Leiden. 'De Strategie van de Aanpassing' gaat over de periode 1876-1975. Otterspeer vertelt over zijn boek in een podcast met…