The thesis is about how auxin and AGC kinases regulate male fertility. The main AGC kinases studied in this thesis is PDK1, PDK2 and AGC1.5, AGC1.7.

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

Microbiome composition of the spermosphere and the rhizosphere of wild and modern bean accessions grown in an agricultural and a native soil from Colombia was characterized by metagenomics and cultivation-dependent approaches.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

This thesis explores how bees and hoverflies are distributed across the Dutch landscape and how ecological and landscape factors shape their occurrence.

Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh

Conventional food supplies procured from rural areas are increasingly vulnerable to disruptions caused by extreme weather, geopolitical instability, and logistical bottlenecks.

In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.

Kunstmatige fotosynthese heeft als doel om via chemische processen zonne-energie om te zettn in brandstof. Semi-kunstmatige fotosynthese is een hybride aanpak waarbij chemische maar ook biotechnologische processen worden gebruikt. Wij hebben als doel om een hybride systeem te ontwikkelen met behulp…

Professor Jan Pieter Abrahams gaat onderzoek doen naar de 3D structuur van biomoleculen om uiteindelijk ziektes als tuberculose, malaria en kanker beter te kunnen begrijpen. Hiervoor heeft de Technologiestichting STW een subsidie toegekend van € 25.000,-

Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

This thesis covers various applications of topology in condensed matter physics and quantum information.

In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…

Agrobacterium-mediated transformation (AMT) has abundantly been used for scientific research for identifying valuable traits.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Promotie

Om te weten hoe hersenen werken, is het essentieel om ze goed in kaart te brengen. Dat blijkt mogelijk met een microscopietechniek waarin Leidse natuurkundigen uitblinken. Deze Amerikaans-Nederlandse doorbraak kan de menselijke zoektocht naar het begrip van hersenfuncties aanzienlijk vooruithelpen.

Op vrijdag 25 mei is de oratie van Tjerk Oosterkamp over zijn leeropdracht 'Experimentele Natuurkunde'.

Bram Koster, hoogleraar Elektron Microscopy, is benoemd tot directeur van NeCEN, de geavanceerde cryo- elektronenmicroscopie faciliteit van de faculteit. Koster wil meer samenwerking op het gebied van onderzoek, nieuwe imaging technieken ontwikkelen en een nieuwe postdoctorale training opzetten voor…

Martina Huber, Jacqueline Labra Munoz onderzoeken de ziekte van Alzheimer. Ze bestudeerden ferritine, ofwel de opslag van ijzer in de hersenen. Een inbalans van ijzer kan een rol spelen bij deze vorm van dementie.

Speciale versterkstoffen kunnen MRI-scanners honderden malen gevoeliger maken. Leidse fysici hebben nu een methode gevonden om hun efficiëntie te toetsen. Gevoeligere MRI-scans kunnen bijvoorbeeld taaislijmziekte of Parkinson begrijpelijker maken. Publicatie op 18 januari in PCCP.

Congres/symposium

Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

De maandelijkse dosis onderzoeksinspiratie van Leiden Science, van onze medewerkers, voor onze medewerkers en alle andere nieuwsgierigen.

Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

Promotor: A. Kros

Promotor: J. A. Bouwstra

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Onderzoekers moeten in een gespecialiseerde omgeving werken zodra ze aan de slag gaan met gevaarlijke bacteriën en virussen. Alleen in laboratoria met een hoog bio-veiligheidsniveau mogen ze deze microben bestuderen. Helaas zijn dure microscopen nodig om de microben goed te bekijken, maar is dat soms…

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

Many galaxy clusters exhibit bright diffuse radio emission that traces the underlying structure of the intracluster medium (ICM).

Promotor: Prof.dr. C.W.J. Beenakker

Geometric phases lead to a nontrivial interference result when an electron's different quantum mechanical paths choices encircle a magnetic coil in an Aharonov-Bohm experiment.

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…