1,721 zoekresultaten voor “a tops eczema” in de Publieke website
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Modelling the dynamics of the innovation process: a data-driven agent-based approach
Promotor: Prof.dr. B.R. Katzy
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Reverse engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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Explicit Computation of the Height of a Gross-Schoen Cycle
Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.
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A chemical biology approach to explore lipid metabolism in neurological disorders
Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.
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Monitoring drought and salinity stress in agriculture by remote sensing for a sustainable future
Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…
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Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
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Value Congruence in a Multinational Corporation
Op 29 Juni 2017 heeft Doris Dull-Zessner haar proefschrift “Value Congruence in a Multinational Corporation” verdedigd. De supervisors zijn prof.dr.mr. J.A.A. Adriaanse and prof.dr. J.I. van der Rest.
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Differentiated instruction in practice: a teacher perspective
Veel docenten in het voortgezet onderwijs houden rekening met verschillen tussen leerlingen. Uit het promotieonderzoek van Saskia Stollman (ICLON) blijkt dat zij hierbij ruimte om te experimenteren en ondersteuning van de school(leiding) nodig hebben.
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Conceptualising organisational forgetting in a crisis context
Wout Broekema benadrukt dat organisaties niet alleen leren van crises, maar ook vergeten, waarbij cruciale kennis en werkwijzen verloren gaan.
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Playing a role – but which one?
Individuen die werken in de publieke sector zien zichzelf geconfronteerd worden met tegenstrijdige waarden, tegenstrijdige eisen en de noodzaak van het dienen van het soms moeilijk definieerbare publieke belang.
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Approaching equilibrium in a dynamic network
This dissertation presents four separate chapters, all striving towards the same goal: to understand dynamic phenomena occurring in dynamic networks and to explore the emergence of equilibrium in a broad sense.
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Presentatie en Q&A tweejarige Educatieve master
Studievoorlichting
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Presentatie en Q&A Education specialisation
Studievoorlichting
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dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros
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The relation between dynamics and activity of phospholipase A/acyltransferase homologs
Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.
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changes for long term impact: optimization of structure kinetic properties: a case of CCR2 antagonists
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
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Towards a Circular Food System: Global Resource Losses, Waste Typologies, and Valorization Pathways
Food waste is a defining inefficiency of the modern food system, with profound implications for resource use, climate change, and circular economy transitions. This dissertation examines food waste through two complementary lenses: the prevention of avoidable food waste and the valorization of unavoidable…
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Molecular inheritance from cloud to disk: a story of complex organics and accretion shocks
Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.
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Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
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A fixed point approach towards stability of delay differential equations with applications to neural networks
Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans
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From the root of variation: A metabolomics perspective to plant soil-feedback
By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.
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Joost blijft assessor: ‘Nog een jaar aan tafel met de top van de faculteit’
Door de pandemie zagen we hem nauwelijks door de wandelgangen lopen. Toch kiest Joost Barendse voor een tweede termijn als assessor. ‘Afgelopen jaar was zo leuk en leerzaam. Dus nog een jaar assessor zijn, daar zeg ik geen nee tegen.’
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The writing culture of ancient Dadan; a description and quantitative analysis of linguistics variation
Fokelien Kootstra verdedigde haar proefschrift op 23 april 2019
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Online Course Anatomy of the Abdomen and the Pelvis: a journey from basic to clinic
In this course, you will explore the organs involved in our food digestion and discover the common causes of abdominal and pelvic pain. The latest graphics and animations will give you new insights and understandings of this part of the body.
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Facets of radio-loud AGN evolution: a LOFAR surveys perspective
Promotor: H.J.A. Rottgering, Co-Promotor: R.J. van Weeren
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‘Als je als vrouw geen voorbeeld ziet van dat de top haalbaar is, ga je buiten de wetenschap kijken’
Het aantal vrouwelijke hoogleraren wil maar niet echt groeien. Waarom is het zo moeilijk om vrouwen aan de wetenschappelijke top te krijgen? Op Internationale Vrouwendag is universitair docent Julia Cramer te gast bij NPO Radio1-programma Spraakmakers. Samen met hoofdredacteur van New Scientist Jim…
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Leidse alumni in 'top 35' in het Advocatenblad
Het vakblad Advocatenblad presenteert '35 onder de 35'; een lijst van de meest veelbelovende (jonge) advocaten van Nederland.
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Spanningen tussen EU-regeringsleiders op Brexit-top
Prof. Luuk van Middelaar sprak op 10 april 2019 in het programma Nieuwsuur over deze spanningen.
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Meer vrouwen in beeld aan de top van de academie
In de Senaatskamer van de Leidse universiteit was een maand lang alleen ruimte voor vrouwen. Het tijdelijke kunstwerk van honderd unieke fotoportretten van vrouwelijke hoogleraren is inmiddels opgeborgen, maar het bestuur van de universiteit neemt een aantal maatregelen om permanent meer ruimte te maken…
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A molecular journey : tales of sublimating ices from hot cores to comets
The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.
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A Matter of Delivery: Nanocarriers and the Engineering of Protective Immunity in Tuberculosis Vaccination
Promotie
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Time Pressure and Teamwork, A Quest for Quality Improvement in Hospitals
Promotie
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A well-established harmony in chaos: from isolated galaxies to galaxy clusters
The origin and evolution of galaxies are closely linked to many different physical phenomena.
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman
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Unveiling the third dimension: vertical structure as a probe of planet formation conditions
Protoplanetary disks are the gas and dust environments where planetary systems form around young stars. Using observations from the Atacama Large Millimeter/submillimeter Array (ALMA) this thesis analyses the gaseous molecular reservoir, using multiple tracers to resolve the 3D structure of protoplanetary…
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They grow up so fast - Stellar accretion in a starburst cluster
When a star is born in our Galaxy, it is quite likely that it has formed within a massive cluster, which hosts numerous high-mass stars bathing their lower mass neighbours in UV radiation.
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Sheltering 10 billion people in a warming and resource-scarce world: challenges and opportunities
Sheltering is an immediate human need and determines well-being andhealth.
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From stress to success; How actinobacteria exploit live without a cell wall
The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.
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Van Vonno, Achieving Party Unity: A Sequential Approach to Why MPs Act in Concert (dissertatie)
Cynthia van Vonno, politicoloog aan de Universiteit Leiden, verklaart in haar proefschrift waarom individuele parlementariers meestemmen met hun fractie.
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Functionalizing monolayer graphene as a proton-selective membrane for direct methanol fuel cells
This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.
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Dutch Post-war Fiction Film through a Lens of Psychoanalysis
Deze week verscheen 'Dutch Post-war Fiction Film through a Lens of Psychoanalysis' van Peter Verstraten bij Amsterdam University Press, het vervolg op Humour and Irony in Dutch Post-war Fiction Film uit 2016. Elk hoofdstuk in zijn 482 pagina's tellende nieuwe studie begint met een titel van Fons Rademakers…
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Unraveling the surface formation of regular and deuterated water in space: a combined laboratory and computational study
Promotor: Prof.dr. H.V.J. Linnartz
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and flow of data: connecting large datasets with machine learning in a drug discovery envirionment
This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…
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Going global to local: achieving agri-food sustainability from a spatially explicit input-output analysis perspective
The global agri-food system plays a critical role in food security and environmental issues.
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Designing 'context-specific' regional innovation policy: a study on the role of regional government in six European regions
Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…
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and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Digging for data: the rise and fall of a Miocene mammal biodiversity hotspot in the Vallès-Penedès (Catalonia, Spain)
The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.