Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

This proposed research uses ego-documents from visual artists that were not intended for publication to reassess the scholarly debate on the demise of the Russian Avant-garde aesthetic in the twenties and early thirties of the 20th century.

Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

The overarching goal of this thesis is to set the foundations, but also make the first essential steps towards establishing a comprehensive, mesoscopic, hydrodynamic theory of epithelial tissues. The stage is set by an exhaustive study of topological defects in passive p-atic liquid crystals, singularities…

Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.

Globally and regionally, biodiversity is declining and there are shifts in species’ occurrences and functional traits.

This thesis addresses the challenge of sustainable urban development by analyzing the interplay between green and grey infrastructure to optimize resource use and ecosystem services.

Plastics have become an integral part of modern society due to their versatility and durability.

Het onderzoek in het natural computing cluster omvat theoretische fundamenten, de ontwikkeling van nieuwe algoritmen en interdisciplinaire toepassingen van natuurlijke computermethoden. De drijvende kracht achter hun onderzoek is de missie om het begrip van natuurlijke systemen als rekenmodellen te…

The global transition toward low-carbon energy systems and the rapid expansion of digital technologies, including artificial intelligence, are reshaping how modern societies produce, move, and process energy and information.

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

Promotores: W. Jiskoot, F. Ossendorp

In this thesis the links between allergy and intestinal health, the gut microbiome (GM), and external factors were studied by exploring the metabolome in longitudinal clinical studies and in vitro models.

Conventional food supplies procured from rural areas are increasingly vulnerable to disruptions caused by extreme weather, geopolitical instability, and logistical bottlenecks.

Bekijk de opbouw van het MSc-programma International Organisation aan Universiteit Leiden. Inclusief semesterindeling, ECTS en cursusbeschrijvingen voor de septemberinstroom in Den Haag.

Verken de wereld van geesteswetenschappen aan de Universiteit Leiden. Ontdek een breed scala aan studies in talen, culturen, geschiedenis, filosofie en meer. Sluit je aan bij een gemeenschap die de wereld begrijpt en vormgeeft.

Het LLP geeft je handvatten om je persoonlijk, professioneel en maatschappelijk te ontwikkelen.

De exacte volgorde en keuze van modules wordt op maat gemaakt voor jouw Ba of Ma opleiding.

Een stevig netwerk van alumni en daaraan verbonden stageplaatsen is erg belangrijk voor onze studenten. Doe mee!

Wil je graag wat extra’s doen naast je studie? Daar is bij de Universiteit Leiden alle ruimte voor.

Lezing

Lezing, Research Seminar Medieval and Early Modern History

Lezing

Lezing, European Union Seminar

Lezing, Research Seminar

Lezing, Research Seminar

Lezing, Research Seminar

Lezing

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

Machine Learning is becoming a more and more substantial technology for industry.

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven

The rapid expansion of research on human gut microbiome in recent decades has highlighted its role in human metabolism, immune regulation, and behavior.