How were the Russians, under early modern conditions, able to incorporate this distant, undeveloped and, because frequent nomadic attacks, dangerous territory? And what role did the Kolyvan-Voskresensk plants play in this process?

Promotor: H.J.M. de Groot

Afgestudeerden van de bachelor Security Studies aan de Universiteit Leiden hebben toegang tot diverse masterprogramma's en uitstekende carrièrekansen. Ontwikkel je als beveiligingsstrateeg en vergroot je kansen op een succesvolle carrière in zowel de publieke als private sector.

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Promotor: S.M. Verduyn Lunel

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

The radio sky harbours both galactic and extragalactic sources of arcminute- to degree-scale emission of various physical origins. To discover extragalactic diffuse emission in the Cosmic Web beyond galaxy clusters, one must image low–surface brightness structures amidst a sea of brighter compact fore-…

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

In this work, we illustrate unconventional approaches towards the fabrication of edge functionalized graphene nanostructures and bidimensional architectures in polymeric and metallic supports, with an outlook towards molecular sensing devices.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.

The LOFAR radio telescope produces petabytes of data every year. Radio Astronomers use complex multi-step pipelines to process this data and produce scientific images.

The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

Women Writing Mexico (WWM) is a network of women and men concerned with the human rights crisis in Mexico and more specifically, with the impact of structural forms of poverty, everyday violence, and discrimination based on gender, race, social class, and ethnicity, that particularly have an impact…

Promotores: Prof.dr. G.A. van der Marel, M. van Heel

Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

We consider the propagation of electrical signals through nerve fibres.

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Promotor: Prof.dr. B.R. Katzy

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

Op 17 november 2021 verdedigde Cyril-Igor Grigorieff het proefschrift 'The Regime for International Air Carrier Liability'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof.dr. V. Correia (University Paris Saclay).

Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

This thesis aims to investigate the effect of tripartite interaction between microbial inoculants, the plant, and herbivore insects on the rhizosphere microbiome and volatilome. We investigated the rhizosphere microbiome and volatilome of tomato plants exposed to insect herbivory and/or inoculated with…

Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.

The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.

This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.

More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Promotor: W. Jiskoot, Co-promotor: H.A. Every

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Promotor: Prof.dr. G.P. van Wezel

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.