In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Op 19 september 2019 verdedigde Lynette Janssen zijn proefschrift 'EU Bank Resolution Framework: A comparative study on the relation with national private law'. Het promotieonderzoek is begeleid door promotoren prof.mr. W.A.K. Rank en prof.mr. M. Haentjens.

In dit onderzoek worden orde isomorfismen en orde antimorfisme bestudeerd in het algemene kader van partieel geordende vector ruimten.

In het hoger onderwijs zijn open leermaterialen beschikbaar die iedereen mag gebruiken, maar ze worden niet zo veel gebruikt.

In dit artikel onderzoeken Malte Reimann en Antonio Cerella hoe politiek en geneeskunde nauw met elkaar verweven zijn geraakt. Ze gebruiken daarbij het gedachtegoed van Roberto Esposito om deze relatie opnieuw te bekijken vanuit het perspectief van een bevestigend biopolitiek.

Deze longitudinale studie is gericht op ontwikkelingsrisico’s bij jonge kinderen met XXY, XXX, XYY, in de leeftijd van 1 tot 6 jaar. Het doel van het onderzoek is zicht te krijgen op de factoren die bijdragen aan risico op gedragsproblemen en psychopathologie.

Deepfakes zijn video’s die gemanipuleerd zijn om twee personen te verwisselen. Ze kunnen moeilijk te onderscheiden zijn van de originele video’s. In onze studie laten we zien dat mensen die meer complotdenken en mensen die meer gebruikmaken van social media beter zijn in het herkennen van deepfakes.

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The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

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In this thesis we push the boundaries of high-resolution imaging at radio frequencies between 100 and 200 MHz. Using the International LOFAR Telescope that spans across Europe we achieve sub-arcsecond angular resolution.

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

Thesis focused on uncovering the underlying mechanisms of the lysosomal storage disorders Gaucher's disease using chemical tools, biochemical assays and lipidomics.

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Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.

Het belangrijkste doel van dit onderzoek was het bevorderen van de aspecten van de symbol sense die studenten in staat stellen algebraïsche formules te doorzien en niet-standaard algebra problemen aan te pakken.

This article studies the influence of framing on preferences for cooperation with the EU.

Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans

Door de groeiende populariteit van zelfregulering door bedrijven om problemen in de leveringsketen aan te pakken, staat maatschappelijk verantwoord ondernemen in het middelpunt van de belangstelling. In dit artikel analyseren Jaroslaw Kantorowicz, Sarah Vandenbroucke en Yvonne Erkens de gedragscodes…

Dit artikel beschrijft het ontstaan van een app die kan helpen om het klimaatbewustzijn en de actie wereldwijd te vergroten.

Ontevreden oudere leraren stoppen regelmatig met lesgeven voordat zij de pensioenleeftijd hebben bereikt. In haar proefschrift pleit Ietje Veldman voor specifieke coaching voor deze groep om hen te behouden voor het onderwijs.

This study seeks to analyse how job stress could be the result of performing administrative tasks

This paper presents the prevalence and characteristics of firearm homicides in Denmark, Finland, the Netherlands, Sweden and Switzerland

Eduard Fosch-Villaronga, universitair hoofddocent bij eLaw, heeft bijgedragen aan 'Cyber–Physical–Human Systems', een boek waarin de nieuwste ontwikkelingen in interacties tussen cyberfysische systemen en mensen worden onderzocht.

Emoties en de psychosociale ontwikkeling van kinderen met en zonder Taal Ontwikkelingsstoornis

The rapid expansion of research on human gut microbiome in recent decades has highlighted its role in human metabolism, immune regulation, and behavior.

Promotie

Dit artikel onderzoekt aanmoediging door leiderschap en psychologische veiligheid als antecedenten van prosociaal regelovertredend gedrag (PSRB).

Promotie

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.

Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

When a star is born in our Galaxy, it is quite likely that it has formed within a massive cluster, which hosts numerous high-mass stars bathing their lower mass neighbours in UV radiation.

With the advent of multicore processors and data centers, computer hardware has become increasingly parallel, allowing one to run multiple pieces of software at the same time on different machines. Coordination of these pieces is best expressed in a coordination language as an explicit interaction protocol…

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Prof. Ton Liefaard en dr. Stephanie Rap (m.m.v. Apollonia Bolscher LL.M.) zijn betrokken bij het ontwikkelen van een training Toolkit en Manual voor het project Improving Juvenile Justice Systems in Europe: Training for Professionals (JUST/2013/FRC/AG).

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

Projecten in de afdeling Industrial Ecology

Heart failure is a major health care problem with high mortality.

With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.