4,421 zoekresultaten voor “security and that” in de Publieke website
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Constraint-Based Analysis of Business Process Models
Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.
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Graphene at fluidic interfaces
In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…
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Development of new chemical tools to study the cannabinoid receptor type 2
The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.
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Tail Regeneration in the Tokay Gecko (Gekko gecko)
Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.
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Fire and grazers in the West African savanna
Promotores: H.A. Udo de Haes, H.H.T. Prins, Co-promotor: H.H. de Iongh
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Genomics applications of nanopore long-read sequencing for small to large sized genomes
In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…
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Soil legacy effects on aboveground plant-insect interactions
In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.
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When data compression and statistics disagree: two frequentist challenges for the minimum description length principle
Promotor: P.D. Grünwald
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Big simulations for big problems
In this thesis we investigate cosmology and the large scale structure of the Universe using cosmological simulations.
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Stress-induced protein dynamic and growth arrest in C. elegans during development
During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).
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Heme biosynthesis and regulation in the filamentous fungus Aspergillus niger
Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel
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The unit residue group
The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.
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Development of automatic image analysis methods for high-throughput and high-content screening
Promotor: Prof.dr. B. van de Water
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers
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Automata-theoretic protocol programming
Promotor: F. Arbab
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Algorithms for the description of molecular sequences
Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros
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Error bounds for discrete tomography
Promotores: K.J. Batenburg, B. Koren
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The Regime for International Air Carrier Liability
Op 17 november 2021 verdedigde Cyril-Igor Grigorieff het proefschrift 'The Regime for International Air Carrier Liability'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof.dr. V. Correia (University Paris Saclay).
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Real-time tomographic reconstruction
With tomography it is possible to reconstruct the interior of an object without destroying.
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Fate, accumulation and impact of metallic nanomaterials in the terrestrial environment
The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.
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Dual Complexes of Semistable Varieties
This thesis is comprised of three chapters covering the theme of studying semistable varieties by looking at their dual combinatorial objects.
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Patterns on Spatially Structured Domains
We consider the propagation of electrical signals through nerve fibres.
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Unraveling modular architecture and domain engineering of carbohydrate-active enzymes: key insights for sustainable bio-based processes
This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…
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Exploring future multi-messenger Galactic astronomy
For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.
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Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
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High-contrast spectroscopy of exoplanet atmospheres
More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.
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creatIef, Creatiever, creaTiefst? Onderzoek naar het belang en de werking van creativiteitstraining bij Bachelor ICT-studenten
This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.
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Collateral Transactions and Shadow Banking
Op 13 oktober 2021 verdedigde Ross Spence het proefschrift 'Collateral Transactions and Shadow Banking'. Het promotieonderzoek is begeleid door promotoren prof.mr. M. Haentjens en prof.dr. A.M. Pacces (UvA).
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Bearing with noise: The effects of highway noise on behaviour and development in zebra finches
Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.
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Neutrinos From the Milky Way
Promotor: Prof.dr. M. de Jong
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Unravelling Glycosylation Reaction Mechanisms
A key step in the synthesis of oligosaccharides and glycoconjugates is the formation of the glycosidic bond.
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting enzyme inhibition
Promotor: Prof.dr. M. Danhof
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Dynamics of coupled quantum systems
Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…
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Quantum computation with Majorana zero modes in superconducting circuits
Promotor: Prof.dr. C.W.J. Beenakker
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bank plant diversity : the interaction between spatiotemporal patterns and agri-environmental management
Promotor: G.R. de Snoo, Co-promotor: C.J.M. Muster
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Reagent Controlled Synthesis of 1,2-cis-Oligosaccharides
This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…
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Effects of slug herbivory on seedling recruitment in Brassica napus and B. rapa
Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Protoplanetary disk anatomy: examining the structure and chemistry of planetary birthplaces with simple molecules
This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.
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Comparative wood anatomy and evolution of Apocynaceae and Sapotaceae
In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.
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wavefront sensors for direct exoplanet imaging: Theory, simulations and on-sky demonstrations
One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…
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Life Cycle Assessment-Based Guidance for development of New Energy Technologies
The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.
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Topology and Geometry in Chiral Liquids
We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.
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The use of computational toxicology in hazard assessment of engineered nanomaterials
Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…
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More JAZ in the orchestration of jasmonate-mediated plant defense
Prof.dr. J. Memelink
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Cavity quantum electrodynamics with quantum dots in microcavities
Promotor: Prof.dr. D. Bouwmeester
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Mind the gap: gas and dust in planet-forming disks
Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond
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Geometry of Vegetation Pattern
One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.