This thesis aims to test in vitro pipelines to rapidly and cost-effectively identify molecular mechanisms that drive adverse outcomes in clinical use.

Promotores: S.J. Edixhoven, P.Parent

A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.

In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.

De Leidse binnenstad hangt er vol mee: muurgedichten. Wie rondloopt, komt poëzie tegen in het Latijnse schrift, maar ook in schriften die voor de gemiddelde Leidenaar minder eenvoudig te begrijpen zijn. In een nieuwe serie video’s vertelt Tijmen Pronk hier meer over.

In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

Binnen het brede netwerk van de Universiteit Leiden neemt het instituut deel aan onderzoek binnen de volgende profileringsgebieden:

Galaxies form and evolve through close interaction with their surroundings. As a result, the heavy elements ('metals') that are synthesized in stars, are found both inside and outside galaxies.

CT scanning of skeletal remains can tell us about how strong or weak a persons bones were and we can relate that back to diet, activity, and reproductive factors.

We investigate how radiation pressure can be used to influence the mechanical motion of a micro-mirror suspended from springs.

In this thesis three different topics in number theory are studied.

Promotor: S.J. Edixhoven Co-promotor: L. van Geemen, P. Parent

Promotor: Erik F. Smets, Co-promotores: Barbara Gravendeel, Niels Raes

Timo Slootweg, associate professor at he department Philosophy of Law, published a chapter about Paul Scholten in

Promotor: Prof.dr. H.L.V. Linnartz

Soil biodiversity is of great importance for the maintenance of multifunctionality in terrestrial ecosystems.

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.

The Low Frequency Array enables studies of low-frequency carbon radio recombination lines with unprecedented sensitivity, spectral and spatial resolution.

Lezing

The AI Collaboration Centre focuses on delivering Smart Computing for Science & Industry. This is reflected in our long-term collaborations with industry and government partners. These partnerships keep our research grounded in real-world applicability while opening new directions within computer sc…

Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Universite Bordeaux I)

How and to what extent the historic house (re-)constructs identity through image-making in China.

Kunst en vrije tijd, Kunst en vrije tijd

Het LAK biedt verschillende schrijfcursussen aan. Maak kennis met de wereld van verhalen verzinnen. Leer de basisvaardigheden van fictie schrijven en leer als schrijver je eigen stem vinden en zet de eerste belangrijke stap van een idee naar een verhaal. Of maak kennis met poëtische technieken. De keuze…

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Hoe meer we leren over een (neuro-)psychologische of lichamelijke aandoening en de hieraan gerelateerde gedragsfactoren, hoe beter we deze niet alleen kunnen signaleren, maar ook behandelen. Het is dus belangrijk dat recente inzichten over (neuro-)psychologische problemen en daaraan gerelateerde gedragsfactoren…

In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.

Promotor: Peter Stevenhagen

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Promotor: F.J. van Lunteren, E. Jorin

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Op 12 januari 2022 verdedigde Mirjam Franke het proefschrift 'Over de grens van de onrechtmatige daad'. Het promotieonderzoek is begeleid door prof.mr. A.G. Castermans en prof.mr. J.H. Crijns.

CML-IA is a database that contains characterisation factors for life cycle impact assessment (LCIA) and is easily read by the CMLCA software program.

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).

The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.

Studievoorlichting, Experience Day

Beneficial plant-associated microbiota, particularly those inhabiting the rhizosphere, contribute substantially to plant health through pathogen suppression, stimulation of plant defence responses, and enhanced nutrient acquisition.

Alumni-activiteit, Lezing

The extensive use of electronic communication channels and other devices has opened new possibilities for collecting data on human behavior. This information is sometimes openly accessible, but largely part of administrative registration systems that are not open to the broader public. The data provides…

Deze colleges zijn in het Engels, u kunt vragen stellen en reageren in het Nederlands.

Een nieuw artikel van Dr. Helen Pluut zal verschijnen in European Journal of Work and Organizational Psychology. Het artikel, dat samen met Marion Büttgen en Jan Ullrich van de Universiteit van Hohenheim is geschreven, heeft implicaties voor organisaties die een duaal laddersysteem hanteren. Zulke systemen…

Kinderen leren meer van digitale prentenboeken dan van traditionele statische boeken. Vooral taalzwakke kinderen begrijpen een verhaal beter dankzij bewegende beelden. Maar interactieve spelletjes werken juist verstorend. Dat concludeert promovenda Zsofia Takacs. Promotie 22 april.