Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

LiDAR is een relatief nieuwe meettechniek waarmee het Actueel Hoogtebestand Nederland het hele land zeer nauwkeurig mee heeft ingemeten. Het grote voordeel van deze manier van meten is dat vegetatie geen belemmering vormt. Hierdoor kunnen ook gebieden waar vegetatie de zichtbaarheid van de ondergrond…

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.

Hieronder vind je een overzicht van hoe onderzoekers van de faculteit Governance and Global Affairs en hun onderzoeken in de media verschijnen, en lees je meer over onderwerpen waar de faculteit zich mee bezighoudt.

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

Antibiotic-resistant bacteria pose a major health threat. Addressing this challenge requires among others the development of new antibacterial compounds. The research described in this thesis focuses on discovering novel antibiotics from soil bacteria, specifically Streptomyces and Paenibacillus.Despite…

This dissertation revolves around the design and implementation of novel instrumentation and related measurement techniques, at the single molecule level, for use in biophysical research. Chapter 1 presents an introduction to the field of fluorescence-based single molecule measurements. In particular,…

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Promotor: Prof.dr. T. Hankemeier

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

Promotor: Prof.dr. H.J.A. Rottgering

Biopolymer sequencing with graphene edge-based tunnel junctions has the potential to overcome current limitations with the third generation of sequencing based on biological nanopores.

We explored how to morphologically classify well-resolved jetted radio-loud active galactic nuclei (RLAGN) in the LOw Frequency Array (LOFAR) Two-metre Sky Survey (LoTSS) using machine learning.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

This thesis investigated miniaturized mass spectrometry (MS)-based analytical methods to address challenges in analyzing biomass-restricted biological samples.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

This dissertation presents new cryptographic protocols, which can be divided into two families.

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

Promotor: Prof.dr. D. Bouwmeester

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

Kinase inhibitors are key therapeutic agents, particularly in oncology, yet their clinical efficacy is often hampered by off-target effects and limited understanding of their cellular target profiles.

Computers worden steeds krachtiger en krijgen steeds ingewikkelder taken. Het Leiden Institute of Advanced Computer Science (LIACS) doet baanbrekend wetenschappelijk onderzoek en past nieuwe vindingen toe in actuele maatschappelijke vraagstukken.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

Binnen Quantum Leiden doen verschillende groepen onderzoek naar quantumnetwerken en quantumsensing.

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

De onderzoeksgroep Diplomacy and Global Affairs richt zich op internationale diplomatie, governance en vergelijkend onderzoek, met aandacht voor thema's zoals de EU, de VN, uitbreiding van de EU, de rechtsstaat, en democratische achteruitgang.

Binnen het Institute of Security and Global Affairs is het onderzoek georganiseerd rond zeven domeinen:

Promotie

Promotie

Promotie

Promotie

Twee hoogleraren die op dezelfde dag hun oratie uitspreken, dat is een zeldzaamheid aan de Universiteit Leiden. Berna Güroğlu en Ellen de Bruijn zijn gespecialiseerd in aanverwante vakgebieden: beiden onderzoeken de invloed van sociale context op hersenprocessen. Güroğlu doet dat bij adolescenten, De…

Het wetenschappelijk onderzoek van de faculteit is georganiseerd binnen verschillende instituten en een aantal centres in Den Haag, stad van vrede, veiligheid en recht.

ISGA in Den Haag biedt bachelor- en masteropleidingen, minoren en onderzoek in security studies, cybersecurity, terrorisme, diplomatie en actuele veiligheidsvraagstukken. Focuspunten: bachelor, master, minoren, onderzoek, security studies, cybersecurity, terrorisme, diplomatie, veiligheidsvraagst…

Lees hier de publicaties die over het Erfgoed Gezocht project zijn verschenen.

Leiden Institute of Advanced Computer Science (LIACS)

Hieronder staan enkele ervaringen van duale promovendi die gepromoveerd zijn met steun van het Dual PhD Centre.

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.