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Leiden University’s Academic Challenge

The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

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IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

The first direct detection of gravitational waves opened the possibility of mapping the Universe via this new and independent messenger.

Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.

This multidisciplinary minor provides students with knowledge on how and why humans became the way they are. The minor focuses on the evolution of the species Homo sapiens from other hominin lineages and animal ancestors, and on the various factors shaping this process. Not only is human evolution of…

Leiden University offers a unique range of summer courses where you can broaden or deepen your knowledge or share your expertise with fellow students. The choice of academic courses is very diverse, ranging from Law, Big Data, Languages and Linguistics to Maths and Natural Sciences, Biology, Biomedical…

The research group Science Communication and Society aims to understand how science communication works to improve the interaction between science and society. Central themes are ‘Bridging the gap between experts and the general public’ and ‘Evaluating Science Communication’.

Quantum computers are a proposed fundamentally new type of computer. They aim to perform some computations much faster than previously possible by exploiting phenomena at the quantum scale, called superposition and entanglement.

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

Transport inspectorates are looking for novel methods to identify dangerous behavior, ultimately to reduce risks associated to the movements of people and goods. We explore a data-driven approach to arrive at smart inspections of vehicles.

Galaxies form and evolve through close interaction with their surroundings. As a result, the heavy elements ('metals') that are synthesized in stars, are found both inside and outside galaxies.

Kiemproject: Hoe kunnen metaforen bijdragen aan betere maatschappelijke betrokkenheid bij quantumwetenschap en -technologie, en welke factoren beïnvloeden de acceptatie of weerstand tegen metaforen bij zowel experts als leken?

Hieronder vind je de antwoorden op een aantal veelgestelde vragen over toelating tot de klinische specialisaties van de Master Psychologie.

Promotie

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De wetenschappelijke onderbouwing van beleid wordt cruciaal geacht voor goed bestuur. Maar ondanks de overvloed aan beschikbare kennis uit onderzoek en evaluaties, weten we nog maar weinig over de daadwerkelijke invloed die dergelijke evidence heeft op overheidsbeleid. Het onderzoeksprogramma ‘Power…

This pioneering project will answer this question by examining migrants through the eyes of the courts between 1600 and 1900. It aims to reveal patterns of continuity and change in: 1. Treatment of migrants by criminal courts; 2. Violence and conflicts between migrants and native born.

Het begrijpen van het veranderende landschap van extremisme in de 21e eeuw.

Computational thinking, programming, and algorithms form the basic of many of the things that are shaping our world, the way we work, interact, organize ourselves, and even spend our free time with social networks, streaming media, and games. And this transformation is far from being complete, it is…

eLaw onderzoekt de rol van het recht in de informatiemaatschappij: hoe kan het recht bijdragen aan een goede werking van informatie- en communicatietechnologie, en het gebruik ervan door burgers, bedrijven en overheden?

Kunst en vrije tijd, Kunst en vrije tijd

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

Promotor: F. Arbab

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

One of the most important correlation functions in physics, especially in cosmology, is the energy density, which describes how much energy is present at each point in spacetime due to matter fields. A key contribution to the energy density of the primordial universe comes from gravitational waves (GWs),…

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

Large carnivore population is globally declining as a result of the fragmentation of habitat, large prey depletion and retaliatory killing by pastoralists.

Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.

Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.

Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

Promotor: W. T. F. den Hollander, F. H. J. Redig

The ability to count is a property not often attributed to materials, despite the abundance of memory in materials. Regardless of how a material stores information, it is often difficult to retrieve exactly ‘what’ a material remembers.

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.