2,677 zoekresultaten voor “discovery of the yuan” in de Publieke website
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Systematics and biogeography of the rattan Calamus javensis complex (Arecaceae, Calamoideae) in Malesia
Calamus javensis is polymorphic. Morphometry and molecular approach resulted in all names used in the complex are regarded as synonyms of C. javensis except C. tenompokensis, which is retained as a distinct species. One variety is here recognized, C. javensis var. polyphyllus (including C. acuminatu…
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Open government and public trust: a new revaluation of the citizen perspective
Hoe beïnvloedt open overheid het publiek vertrouwen?
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Patient-derived models of breast cancer: a breakthrough story of the duct
To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…
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Validity in teacher assessment. An exploration of the judgement processes of assessors
In dit proefschrift staat validiteit in de beoordeling van docentcompetenties centraal.
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Van Ham, Thomassen, Aarts & Andeweg (eds), Myth and Reality of the Legitimacy Crisis
Beleeft de democratie daadwerkelijk een legitimiteitscrisis? De auteurs toetsen de stelling dat gevestigde democratieën aan legitimiteit inboeten. Voorts bekijken zij in hoeverre bestaande theorieën de legitimiteitscrisis zien en verklaren. Ook onderzoeken zij nieuwe mogelijkheden voor het bestuderen…
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Antiquities of the rainforest: evolution of mycoheterotrophic angiosperms growing on Glomeromycota
Promotor: Prof.dr. E.F. Smets
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Preclinical Insights into Early Psychopharmacology Trials: Application of the IB-Derisk Analyser Tool
Promotie
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Towards Implementation of the Tumour-Stroma Ratio in Colorectal Cancer
Promotie
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Erik Danen benoemd tot hoogleraar Cancer drug target discovery
Met ingang van 1 april 2018 is Erik Danen benoemd tot hoogleraar Cancer drug target discovery bij het Leiden Academic Centre for Drug Research (LACDR). Zijn vakgebied is celbiologie van kanker, waarin hij zich richt op de achterliggende mechanismen bij uitzaaiingen en resistentie voor behandelingen.
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NMR structural studies of protein-small molecule interactions
Promotor: Prof.dr. M. Ubbink, Co-promotor: G. Siegal
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Course: Introduction to the Archaeology of the Book
The Summer School History of the Book, organized by the Allard Pierson Museum, introduces a new course in English: Introduction to the Archaeology of the Book, taught by Prof. Malcolm Walsby (2-6 September 2024).
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Witnessing the Process of Bacterial Cell Death: Novel Antimicrobials and Their Mechanisms of Action
This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…
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The Future of Paleography, Paleography of the Future
The first congress of the UU Paleohub, 'The Future of Paleography, Paleography of the Future'. 10 april 2025
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Summer School on the History of the Book
Van 21 augustus tot en met 8 september zijn de workshops en cursus van de jaarlijkse Summer School on the History of the Book van het Allard Pierson en de vakgroep Boekwetenschap. Drie weken lang is er elke werkdag een cursus, workshop of lezing over thema’s die te maken hebben met de geschiedenis van…
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Furthering the fight against impunity in Latin America: the contributions of the Inter-American Court of Human Rights to domestic accountability
Op 3 december 2019 verdedigde Hanna Bosdriesz haar proefschrift 'Furthering the fight against impunity in Latin America: the contributions of the Inter-American Court of Human Rights to domestic accountability processes'. Het promotieonderzoek is begeleid door promotoren prof.dr. L.J. van den Herik…
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The Role of Efficient Causation in Aristotle’s Philosophy: Ensuring the Continuity and Coherence of the Cosmos within a Teleological Framework
Promotie
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LED3 & LUCID Drug Discovery Meeting
Congres/symposium
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Discovering the preference hypervolume: an interactive model for real world computational co-creativity
In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Structural changes in single chromatin fibers induced by tension and torsion
Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
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Non-invasive biomarkers for inflammatory skin diseases: towards systems dermatology
Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…
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Hunting dark matter with X-rays
Promotor: A. Achúcarro Co-promotor: A. Boyarsky
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Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
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Chemical tools to modulate endocannabinoid biosynthesis
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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Race Of The Classics: het Reesgevoel forever
De Race of the Classics is het grootste studentenzeilevenement van Europa. Dit jaar werd de race van 4 t/m 10 april gevaren, met achttien schepen. Daan Kok, tweedejaars Fiscaal recht voer mee in team Leiden op de Tecla, een logger uit 2015. En legt uit hoe het Reesgevoel ontstaat.
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Stem op Discoverer of the Year
Scott Waitukaitus is namens LION genomineerd als Discoverer of the Year 2017. Breng snel je stem uit!
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Vote for Discoverer of the Year 2017
Suzan Verberne is nominated by the Leiden Institute of Advanced Computer Science (LIACS) to be granted the C.J. Kok Public Award, also known as the award for the ‘Discoverer of the Year’.
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Astronoom Joe Callingham getuigt tegen killer-sterren in nieuwe show op Discovery
Op vrijdagavond 17 september is de Leidse astronoom Joe Callingham te zien in een nieuwe serie op Discovery. ‘Killers of The Cosmos’ gaat over krachten in het heelal die ons bestaan kunnen bedreigen. Asteroïden, kosmisch puin, elektromagnetische wapens… De show behandelt elke bedreiging als potentiële…
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CfP 2023 FIDEM Congress: The Medieval Book Through the Lens of the Librarian (Basel)
The 7th European Congress of Medieval Studies of the Fédération Internationale des Instituts d’Études Médiévales (FIDEM) will be organized by the Department of Arts, Media, and Philosophy of the University of Basel, Switzerland. There is a number of slots for papers (20 minutes) and special sessions…
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Stem op Discoverer of the Year
Stem voor de Ontdekker van het jaar 2017! Wie van deze onderzoekers verdient volgens jou een prijs voor zijn of haar werk? Vanaf nu kan je stemmen!
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Poster presentations: Future of Paleography, Paleography of the Future
Call for poster presentations: Future of Paleography, Paleography of the Future. 10 April 2025, Utrecht.
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Marina Gorostiola GonzálezWiskunde en Natuurwetenschappen
m.gorostiola.gonzalez@lacdr.leidenuniv.nl | 071 5272727
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Eani LachmansinghWiskunde en Natuurwetenschappen
e.t.lachmansingh@liacs.leidenuniv.nl | 071 5272727
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Boeklancering 'The United Nations Convention on the Rights of the Child’
Het boek 'The United Nations Convention on the Rights of the Child' is het resultaat van internationale wetenschappelijke congres - '25 Years CRC' – dat plaatsvond in november 2014 in Leiden ter gelegenheid van de 25e verjaardag van het VN-Kinderrechtenverdrag.
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Chemical tools to monitor and control proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Anti-microbial and Anti-biofilm compounds From Indonesian Medicinal Plants
Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert
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Microglial lipid metabolism: a delicate balance
Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.
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Archief
Op deze pagina vindt u de opnames van de online This Week's Discoveries vanaf 12 mei 2020 en een lijst sprekers vanaf oktober 2015.
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Archief
Op deze pagina vind je de opnames van de Tuesday Talks sinds april 2025. Ook de opnames van de voorloper van de Tuesday Talks, This Week’s Discoveries, zijn hier te vinden
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Infographic eindrapport State of the Art Crisisbeheersing 2
State of the Art Crisisbeheersing 2